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Evaluation of Tumor DNA Sequencing Results in Patients with Gastric and Gastroesophageal Junction Adenocarcinoma Stratified by TP53 Mutation Status

BACKGROUND: Gastric cancer (GC) and gastroesophageal junction adenocarcinomas (GEJ) are molecularly diverse. TP53 is the most frequently altered gene with approximately 50% of patients harboring mutations. This qualitative study describes the distinct genomic alterations in GCs and GEJs stratified b...

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Detalles Bibliográficos
Autores principales: Wood, Anthony C, Zhang, Yonghong, Mo, Qianxing, Cen, Ling, Fontaine, Jacques, Hoffe, Sarah E, Frakes, Jessica, Dineen, Sean P, Pimiento, Jose M, Walko, Christine M, Mehta, Rutika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982441/
https://www.ncbi.nlm.nih.gov/pubmed/35380714
http://dx.doi.org/10.1093/oncolo/oyac018