Cargando…

Case Report: Early Resection of Pheochromocytoma in a Patient With Cardiogenic Shock Due to Pheochromocytoma-Induced Cardiomyopathy With Extracorporeal Life Support

BACKGROUND: Pheochromocytoma-induced cardiomyopathy is a rare but potentially life-threatening complication of pheochromocytoma. It mimics the patterns of stress-induced cardiomyopathy. In severe cases, patients can develop refractory cardiogenic shock, which might require mechanical circulatory sup...

Descripción completa

Detalles Bibliográficos
Autores principales: Lyu, Ting, Niu, Jianhua, Liu, Zhihai, Li, Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982527/
https://www.ncbi.nlm.nih.gov/pubmed/35391844
http://dx.doi.org/10.3389/fcvm.2022.788644
_version_ 1784681830554796032
author Lyu, Ting
Niu, Jianhua
Liu, Zhihai
Li, Tong
author_facet Lyu, Ting
Niu, Jianhua
Liu, Zhihai
Li, Tong
author_sort Lyu, Ting
collection PubMed
description BACKGROUND: Pheochromocytoma-induced cardiomyopathy is a rare but potentially life-threatening complication of pheochromocytoma. It mimics the patterns of stress-induced cardiomyopathy. In severe cases, patients can develop refractory cardiogenic shock, which might require mechanical circulatory support. CASE PRESENTATION: We presented a case of 54-year-old female who developed refractory cardiogenic shock, following an elective orthopaedic surgery complicated by cardiac arrest, requiring veno-arterial extracorporeal membrane oxygenation (VA-ECMO) support. After urgent coronary catheterisation revealed normal coronary arteries, further evaluation of the aetiology of cardiogenic shock revealed pheochromocytoma. With a diagnosis of pheochromocytoma-induced cardiomyopathy, the patient had accelerated preoperative alpha adrenergic blockade preparation for a total of 6 days and subsequently had the tumour removed under VA-ECMO support. Postoperatively, the patient recovered well and was off ECMO support and extubated a few days later. The optimal management of pheochromocytoma-induced cardiomyopathy, especially for severe cases, is still unclear. Indeed, some cases will require mechanical circulatory support to allow left ventricular function recovery. But our case also showed that it was possible to introduce alpha blockade safely whilst the patient is on VA-ECMO and has the pheochromocytoma removed with VA-ECMO support after accelerated preoperative preparation.
format Online
Article
Text
id pubmed-8982527
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-89825272022-04-06 Case Report: Early Resection of Pheochromocytoma in a Patient With Cardiogenic Shock Due to Pheochromocytoma-Induced Cardiomyopathy With Extracorporeal Life Support Lyu, Ting Niu, Jianhua Liu, Zhihai Li, Tong Front Cardiovasc Med Cardiovascular Medicine BACKGROUND: Pheochromocytoma-induced cardiomyopathy is a rare but potentially life-threatening complication of pheochromocytoma. It mimics the patterns of stress-induced cardiomyopathy. In severe cases, patients can develop refractory cardiogenic shock, which might require mechanical circulatory support. CASE PRESENTATION: We presented a case of 54-year-old female who developed refractory cardiogenic shock, following an elective orthopaedic surgery complicated by cardiac arrest, requiring veno-arterial extracorporeal membrane oxygenation (VA-ECMO) support. After urgent coronary catheterisation revealed normal coronary arteries, further evaluation of the aetiology of cardiogenic shock revealed pheochromocytoma. With a diagnosis of pheochromocytoma-induced cardiomyopathy, the patient had accelerated preoperative alpha adrenergic blockade preparation for a total of 6 days and subsequently had the tumour removed under VA-ECMO support. Postoperatively, the patient recovered well and was off ECMO support and extubated a few days later. The optimal management of pheochromocytoma-induced cardiomyopathy, especially for severe cases, is still unclear. Indeed, some cases will require mechanical circulatory support to allow left ventricular function recovery. But our case also showed that it was possible to introduce alpha blockade safely whilst the patient is on VA-ECMO and has the pheochromocytoma removed with VA-ECMO support after accelerated preoperative preparation. Frontiers Media S.A. 2022-03-21 /pmc/articles/PMC8982527/ /pubmed/35391844 http://dx.doi.org/10.3389/fcvm.2022.788644 Text en Copyright © 2022 Lyu, Niu, Liu and Li. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Lyu, Ting
Niu, Jianhua
Liu, Zhihai
Li, Tong
Case Report: Early Resection of Pheochromocytoma in a Patient With Cardiogenic Shock Due to Pheochromocytoma-Induced Cardiomyopathy With Extracorporeal Life Support
title Case Report: Early Resection of Pheochromocytoma in a Patient With Cardiogenic Shock Due to Pheochromocytoma-Induced Cardiomyopathy With Extracorporeal Life Support
title_full Case Report: Early Resection of Pheochromocytoma in a Patient With Cardiogenic Shock Due to Pheochromocytoma-Induced Cardiomyopathy With Extracorporeal Life Support
title_fullStr Case Report: Early Resection of Pheochromocytoma in a Patient With Cardiogenic Shock Due to Pheochromocytoma-Induced Cardiomyopathy With Extracorporeal Life Support
title_full_unstemmed Case Report: Early Resection of Pheochromocytoma in a Patient With Cardiogenic Shock Due to Pheochromocytoma-Induced Cardiomyopathy With Extracorporeal Life Support
title_short Case Report: Early Resection of Pheochromocytoma in a Patient With Cardiogenic Shock Due to Pheochromocytoma-Induced Cardiomyopathy With Extracorporeal Life Support
title_sort case report: early resection of pheochromocytoma in a patient with cardiogenic shock due to pheochromocytoma-induced cardiomyopathy with extracorporeal life support
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982527/
https://www.ncbi.nlm.nih.gov/pubmed/35391844
http://dx.doi.org/10.3389/fcvm.2022.788644
work_keys_str_mv AT lyuting casereportearlyresectionofpheochromocytomainapatientwithcardiogenicshockduetopheochromocytomainducedcardiomyopathywithextracorporeallifesupport
AT niujianhua casereportearlyresectionofpheochromocytomainapatientwithcardiogenicshockduetopheochromocytomainducedcardiomyopathywithextracorporeallifesupport
AT liuzhihai casereportearlyresectionofpheochromocytomainapatientwithcardiogenicshockduetopheochromocytomainducedcardiomyopathywithextracorporeallifesupport
AT litong casereportearlyresectionofpheochromocytomainapatientwithcardiogenicshockduetopheochromocytomainducedcardiomyopathywithextracorporeallifesupport