Can the personalized medicine approach contribute in controlling tuberculosis in general and India in particular?

Poor drug compliance and drug-resistant Mycobacterium tuberculosis are the two principal obstacles in controlling tuberculosis (TB) in endemic regions including India, which has contributed the most to global TB burden. We argue here that a personalized medicine approach, to start with the N-acetyl...

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Detalles Bibliográficos
Autores principales: Khan, Nikhat, Das, Aparup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982531/
https://www.ncbi.nlm.nih.gov/pubmed/35694414
http://dx.doi.org/10.1093/pcmedi/pbaa021
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author Khan, Nikhat
Das, Aparup
author_facet Khan, Nikhat
Das, Aparup
author_sort Khan, Nikhat
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description Poor drug compliance and drug-resistant Mycobacterium tuberculosis are the two principal obstacles in controlling tuberculosis (TB) in endemic regions including India, which has contributed the most to global TB burden. We argue here that a personalized medicine approach, to start with the N-acetyl transferase-2–isoniazid (NAT2–INH) model, could be a step forward in dealing with both these limitations in controlling TB in India.
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spelling pubmed-89825312022-06-10 Can the personalized medicine approach contribute in controlling tuberculosis in general and India in particular? Khan, Nikhat Das, Aparup Precis Clin Med Perspective Poor drug compliance and drug-resistant Mycobacterium tuberculosis are the two principal obstacles in controlling tuberculosis (TB) in endemic regions including India, which has contributed the most to global TB burden. We argue here that a personalized medicine approach, to start with the N-acetyl transferase-2–isoniazid (NAT2–INH) model, could be a step forward in dealing with both these limitations in controlling TB in India. Oxford University Press 2020-06-04 /pmc/articles/PMC8982531/ /pubmed/35694414 http://dx.doi.org/10.1093/pcmedi/pbaa021 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of the West China School of Medicine & West China Hospital of Sichuan University. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Perspective
Khan, Nikhat
Das, Aparup
Can the personalized medicine approach contribute in controlling tuberculosis in general and India in particular?
title Can the personalized medicine approach contribute in controlling tuberculosis in general and India in particular?
title_full Can the personalized medicine approach contribute in controlling tuberculosis in general and India in particular?
title_fullStr Can the personalized medicine approach contribute in controlling tuberculosis in general and India in particular?
title_full_unstemmed Can the personalized medicine approach contribute in controlling tuberculosis in general and India in particular?
title_short Can the personalized medicine approach contribute in controlling tuberculosis in general and India in particular?
title_sort can the personalized medicine approach contribute in controlling tuberculosis in general and india in particular?
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982531/
https://www.ncbi.nlm.nih.gov/pubmed/35694414
http://dx.doi.org/10.1093/pcmedi/pbaa021
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