Elevated H3K4me3 Through MLL2-WDR82 upon Hyperglycemia Causes Jagged Ligand Dependent Notch Activation to Interplay with Differentiation State of Endothelial Cells

Endothelial-to-mesenchymal transition (EndMT) is a hallmark of diabetes-associated vascular complications. Epigenetic mechanisms emerged as one of the key pathways to regulate diabetes-associated complications. In the current study, we aimed to determine how abrupt changes in histone 3 lysine 4 tri-...

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Detalles Bibliográficos
Autores principales: Pandya Thakkar, Niyati, Pereira, Beatriz Maria Veloso, Katakia, Yash T., Ramakrishnan, Shyam Kumar, Thakar, Sumukh, Sakhuja, Ashima, Rajeev, Gayathry, Soorya, S., Thieme, Karina, Majumder, Syamantak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982561/
https://www.ncbi.nlm.nih.gov/pubmed/35392173
http://dx.doi.org/10.3389/fcell.2022.839109

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