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miR-155-overexpressing monocytes resemble HLA(high)ISG15(+) synovial tissue macrophages from patients with rheumatoid arthritis and induce polyfunctional CD4(+) T-cell activation
MicroRNAs (miRs) are known to regulate pro-inflammatory effector functions of myeloid cells, and miR dysregulation is implicated in rheumatoid arthritis (RA), a condition characterized by inflammation and destruction of the joints. We showed previously that miR-155 is increased in myeloid cells in R...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982969/ https://www.ncbi.nlm.nih.gov/pubmed/35020867 http://dx.doi.org/10.1093/cei/uxab016 |