miR-155-overexpressing monocytes resemble HLA(high)ISG15(+) synovial tissue macrophages from patients with rheumatoid arthritis and induce polyfunctional CD4(+) T-cell activation

MicroRNAs (miRs) are known to regulate pro-inflammatory effector functions of myeloid cells, and miR dysregulation is implicated in rheumatoid arthritis (RA), a condition characterized by inflammation and destruction of the joints. We showed previously that miR-155 is increased in myeloid cells in R...

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Detalles Bibliográficos
Autores principales: Olsson, Anton M, Povoleri, Giovanni A M, Somma, Domenico, Ridley, Michael L, Rizou, Tatiana, Lalnunhlimi, Sylvine, Macdonald, Lucy, Rajasekhar, Megha, Martinez-Nunez, Rocio T, Kurowska-Stolarska, Mariola, Taams, Leonie S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982969/
https://www.ncbi.nlm.nih.gov/pubmed/35020867
http://dx.doi.org/10.1093/cei/uxab016

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