Cargando…
Recurrent moderate hypoglycemia accelerates the progression of Alzheimer’s disease through impairment of the TRPC6/GLUT3 pathway
Currently, the most effective strategy for dealing with Alzheimer’s disease (AD) is delaying the onset of dementia. Severe hypoglycemia is strongly associated with dementia; however, the effects of recurrent moderate hypoglycemia (RH) on the progression of cognitive deficits in patients with diabete...
Autores principales: | He, Chengkang, Li, Qiang, Cui, Yuanting, Gao, Peng, Shu, Wentao, Zhou, Qing, Wang, Lijuan, Li, Li, Lu, Zongshi, Zhao, Yu, Ma, Huan, Chen, Xiaowei, Jia, Hongbo, Zheng, Hongting, Yang, Gangyi, Liu, Daoyan, Tepel, Martin, Zhu, Zhiming |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983129/ https://www.ncbi.nlm.nih.gov/pubmed/35077394 http://dx.doi.org/10.1172/jci.insight.154595 |
Ejemplares similares
-
Low‐glucose‐sensitive TRPC6 dysfunction drives hypoglycemia‐induced cognitive impairment in diabetes
por: He, Chengkang, et al.
Publicado: (2020) -
Sodium‐Glucose Cotransporter 2 Inhibitor Canagliflozin Antagonizes Salt‐Sensitive Hypertension Through Modifying Transient Receptor Potential Channels 3 Mediated Vascular Calcium Handling
por: Zhao, Yu, et al.
Publicado: (2022) -
Non-insulin determinant pathways maintain glucose homeostasis upon metabolic surgery
por: Lu, Zongshi, et al.
Publicado: (2018) -
Activation of Transient Receptor Potential Melastatin Subtype 8 Attenuates Cold‐Induced Hypertension Through Ameliorating Vascular Mitochondrial Dysfunction
por: Xiong, Shiqiang, et al.
Publicado: (2017) -
Gastrointestinal Intervention Ameliorates High Blood Pressure Through Antagonizing Overdrive of the Sympathetic Nerve in Hypertensive Patients and Rats
por: Zhang, Hexuan, et al.
Publicado: (2014)