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Adipocyte-derived PGE(2) is required for intermittent fasting–induced Treg proliferation and improvement of insulin sensitivity
The intermittent fasting (IF) diet has profound benefits for diabetes prevention. However, the precise mechanisms underlying IF’s beneficial effects remain poorly defined. Here, we show that the expression levels of cyclooxygenase-2 (COX-2), an enzyme that produces prostaglandins, are suppressed in...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983131/ https://www.ncbi.nlm.nih.gov/pubmed/35260536 http://dx.doi.org/10.1172/jci.insight.153755 |