Adipocyte-derived PGE(2) is required for intermittent fasting–induced Treg proliferation and improvement of insulin sensitivity

The intermittent fasting (IF) diet has profound benefits for diabetes prevention. However, the precise mechanisms underlying IF’s beneficial effects remain poorly defined. Here, we show that the expression levels of cyclooxygenase-2 (COX-2), an enzyme that produces prostaglandins, are suppressed in...

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Detalles Bibliográficos
Autores principales: Wang, Chunqing, Zhang, Xing, Luo, Liping, Luo, Yan, Yang, Xin, Ding, Xiaofeng, Wang, Lu, Le, Huyen, Feldman, Lily Elizabeth R., Men, Xuebo, Yan, Cen, Huang, Wendong, Feng, Yingmei, Liu, Feng, Yang, Xuexian O., Liu, Meilian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983131/
https://www.ncbi.nlm.nih.gov/pubmed/35260536
http://dx.doi.org/10.1172/jci.insight.153755

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