CD8(+) T cell–derived IL-13 increases macrophage IL-10 to resolve neuropathic pain

Understanding the endogenous mechanisms regulating resolution of pain may identify novel targets for treatment of chronic pain. Resolution of chemotherapy-induced peripheral neuropathy (CIPN) after treatment completion depends on CD8(+) T cells and on IL-10 produced by other cells. Using Rag2(–/–) m...

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Detalles Bibliográficos
Autores principales: Singh, Susmita K., Krukowski, Karen, Laumet, Geoffroy O., Weis, Drew, Alexander, Jenolyn F., Heijnen, Cobi J., Kavelaars, Annemieke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983134/
https://www.ncbi.nlm.nih.gov/pubmed/35260535
http://dx.doi.org/10.1172/jci.insight.154194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983134/
https://www.ncbi.nlm.nih.gov/pubmed/35260535
http://dx.doi.org/10.1172/jci.insight.154194

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