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CD8(+) T cell–derived IL-13 increases macrophage IL-10 to resolve neuropathic pain
Understanding the endogenous mechanisms regulating resolution of pain may identify novel targets for treatment of chronic pain. Resolution of chemotherapy-induced peripheral neuropathy (CIPN) after treatment completion depends on CD8(+) T cells and on IL-10 produced by other cells. Using Rag2(–/–) m...
Autores principales: | Singh, Susmita K., Krukowski, Karen, Laumet, Geoffroy O., Weis, Drew, Alexander, Jenolyn F., Heijnen, Cobi J., Kavelaars, Annemieke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983134/ https://www.ncbi.nlm.nih.gov/pubmed/35260535 http://dx.doi.org/10.1172/jci.insight.154194 |
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