Immunoglobulin A nephropathy is characterized by anticommensal humoral immune responses

IgA nephropathy (IgAN) is a leading cause of kidney failure, yet little is known about the immunopathogenesis of this disease. IgAN is characterized by deposition of IgA in the kidney glomeruli, but the source and stimulus for IgA production are not known. Clinical and experimental data suggest a ro...

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Detalles Bibliográficos
Autores principales: Currie, Elissa G., Coburn, Bryan, Porfilio, Elisa A., Lam, Ping, Rojas, Olga L., Novak, Jan, Yang, Stuart, Chowdhury, Raad B., Ward, Lesley A., Wang, Pauline W., Khaleghi, Khashayar, An, James, Crome, Sarah Q., Hladunewich, Michelle A., Barbour, Sean J., Cattran, Daniel C., Parekh, Rulan S., Licht, Christoph, John, Rohan, Kaul, Rupert, Croitoru, Kenneth, Gray-Owen, Scott D., Guttman, David S., Gommerman, Jennifer L., Reich, Heather N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983137/
https://www.ncbi.nlm.nih.gov/pubmed/35133979
http://dx.doi.org/10.1172/jci.insight.141289

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