The molecular chaperone GRP170 protects against ER stress and acute kidney injury in mice

Molecular chaperones are responsible for maintaining cellular homeostasis, and one such chaperone, GRP170, is an endoplasmic reticulum (ER) resident that oversees both protein biogenesis and quality control. We previously discovered that GRP170 regulates the degradation and assembly of the epithelia...

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Detalles Bibliográficos
Autores principales: Porter, Aidan W., Nguyen, Diep N., Clayton, Dennis R., Ruiz, Wily G., Mutchler, Stephanie M., Ray, Evan C., Marciszyn, Allison L., Nkashama, Lubika J., Subramanya, Arohan R., Gingras, Sebastien, Kleyman, Thomas R., Apodaca, Gerard, Hendershot, Linda M., Brodsky, Jeffrey L., Buck, Teresa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983141/
https://www.ncbi.nlm.nih.gov/pubmed/35104250
http://dx.doi.org/10.1172/jci.insight.151869

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