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PLG nanoparticles target fibroblasts and MARCO(+) monocytes to reverse multiorgan fibrosis
Systemic sclerosis (SSc) is a chronic, multisystem orphan disease with a highly variable clinical course, high mortality rate, and a poorly understood complex pathogenesis. We have identified an important role for a subpopulation of monocytes and macrophages characterized by surface expression of th...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Clinical Investigation
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983146/ https://www.ncbi.nlm.nih.gov/pubmed/35104243 http://dx.doi.org/10.1172/jci.insight.151037 |