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Epidural anesthesia in dogs undergoing hindlimb orthopedic surgery: effects of two injection sites

This prospective clinical trial evaluated the effects of epidural anesthesia (EA) placed at the lumbosacral compared to the L5–L6 junction in dogs undergoing hindlimb orthopedic surgery. In all, 98 dogs were randomly assigned to receive injection at either L7–S1 (LS group) or L5–L6 (LL group) at the...

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Autores principales: SAROTTI, Diego, ALA, Ugo, FRANCI, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983285/
https://www.ncbi.nlm.nih.gov/pubmed/35067493
http://dx.doi.org/10.1292/jvms.21-0289
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author SAROTTI, Diego
ALA, Ugo
FRANCI, Paolo
author_facet SAROTTI, Diego
ALA, Ugo
FRANCI, Paolo
author_sort SAROTTI, Diego
collection PubMed
description This prospective clinical trial evaluated the effects of epidural anesthesia (EA) placed at the lumbosacral compared to the L5–L6 junction in dogs undergoing hindlimb orthopedic surgery. In all, 98 dogs were randomly assigned to receive injection at either L7–S1 (LS group) or L5–L6 (LL group) at the same local anesthetic regimen (1 mg/kg bupivacaine 0.5% and 0.1 mg/kg morphine 1%). Fentanyl (1 µg/kg) was the intraoperative rescue analgesia (iRA) administered if mean arterial pressure increased by 30% above pre-stimulation value. Procedural failure, iRA, hypotension, motor block resolution, and postoperative side effects were recorded. There were 7/47 (15%) epidural procedural failures in the LS group and 8/51 (16%) (P=1.00) in the LL group; iRA was administered in 21/40 (52%) LS group dogs and in 13/43 (30%) LL group dogs, respectively (P=0.047). The incidence of hypotension was 10/40 (25%) and 16/43 (37%) in the LS group and the LL group, respectively (P=0.25). Proprioceptive residual deficit at 8 hr after EA was recorded in 3/26 (12%) in group LS dogs and in 13/26 (50%) group LL dogs, respectively (P=0.01). The proprioceptive residual deficit at 24 hr in one dog (LL group) resolved within 36 hr. No episodes of postoperative urinary retention, pruritus or neurological damage were recorded. The L5–L6 EA decreased significantly iRA but delays the proprioceptive recovery time. Further studies are needed to determine whether a lower bupivacaine dose reduces the duration of the residual block retaining the same incidence of iRA.
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spelling pubmed-89832852022-04-14 Epidural anesthesia in dogs undergoing hindlimb orthopedic surgery: effects of two injection sites SAROTTI, Diego ALA, Ugo FRANCI, Paolo J Vet Med Sci Surgery This prospective clinical trial evaluated the effects of epidural anesthesia (EA) placed at the lumbosacral compared to the L5–L6 junction in dogs undergoing hindlimb orthopedic surgery. In all, 98 dogs were randomly assigned to receive injection at either L7–S1 (LS group) or L5–L6 (LL group) at the same local anesthetic regimen (1 mg/kg bupivacaine 0.5% and 0.1 mg/kg morphine 1%). Fentanyl (1 µg/kg) was the intraoperative rescue analgesia (iRA) administered if mean arterial pressure increased by 30% above pre-stimulation value. Procedural failure, iRA, hypotension, motor block resolution, and postoperative side effects were recorded. There were 7/47 (15%) epidural procedural failures in the LS group and 8/51 (16%) (P=1.00) in the LL group; iRA was administered in 21/40 (52%) LS group dogs and in 13/43 (30%) LL group dogs, respectively (P=0.047). The incidence of hypotension was 10/40 (25%) and 16/43 (37%) in the LS group and the LL group, respectively (P=0.25). Proprioceptive residual deficit at 8 hr after EA was recorded in 3/26 (12%) in group LS dogs and in 13/26 (50%) group LL dogs, respectively (P=0.01). The proprioceptive residual deficit at 24 hr in one dog (LL group) resolved within 36 hr. No episodes of postoperative urinary retention, pruritus or neurological damage were recorded. The L5–L6 EA decreased significantly iRA but delays the proprioceptive recovery time. Further studies are needed to determine whether a lower bupivacaine dose reduces the duration of the residual block retaining the same incidence of iRA. The Japanese Society of Veterinary Science 2022-01-24 2022-03 /pmc/articles/PMC8983285/ /pubmed/35067493 http://dx.doi.org/10.1292/jvms.21-0289 Text en ©2022 The Japanese Society of Veterinary Science https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Surgery
SAROTTI, Diego
ALA, Ugo
FRANCI, Paolo
Epidural anesthesia in dogs undergoing hindlimb orthopedic surgery: effects of two injection sites
title Epidural anesthesia in dogs undergoing hindlimb orthopedic surgery: effects of two injection sites
title_full Epidural anesthesia in dogs undergoing hindlimb orthopedic surgery: effects of two injection sites
title_fullStr Epidural anesthesia in dogs undergoing hindlimb orthopedic surgery: effects of two injection sites
title_full_unstemmed Epidural anesthesia in dogs undergoing hindlimb orthopedic surgery: effects of two injection sites
title_short Epidural anesthesia in dogs undergoing hindlimb orthopedic surgery: effects of two injection sites
title_sort epidural anesthesia in dogs undergoing hindlimb orthopedic surgery: effects of two injection sites
topic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983285/
https://www.ncbi.nlm.nih.gov/pubmed/35067493
http://dx.doi.org/10.1292/jvms.21-0289
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