Cargando…
SARS-CoV-2 impairs the disassembly of stress granules and promotes ALS-associated amyloid aggregation
The nucleocapsid (N) protein of SARS-CoV-2 has been reported to have a high ability of liquid-liquid phase separation, which enables its incorporation into stress granules (SGs) of host cells. However, whether SG invasion by N protein occurs in the scenario of SARS-CoV-2 infection is unknow, neither...
Autores principales: | Li, Yichen, Lu, Shuaiyao, Gu, Jinge, Xia, Wencheng, Zhang, Shengnan, Zhang, Shenqing, Wang, Yan, Zhang, Chong, Sun, Yunpeng, Lei, Jian, Liu, Cong, Su, Zhaoming, Yang, Juntao, Peng, Xiaozhong, Li, Dan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Higher Education Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983322/ https://www.ncbi.nlm.nih.gov/pubmed/35384603 http://dx.doi.org/10.1007/s13238-022-00905-7 |
Ejemplares similares
-
Hsp70 exhibits a liquid-liquid phase separation ability and chaperones condensed FUS against amyloid aggregation
por: Li, Yichen, et al.
Publicado: (2022) -
Molecular structure of an amyloid fibril formed by FUS low-complexity domain
por: Sun, Yunpeng, et al.
Publicado: (2021) -
Reversible amyloids of pyruvate kinase couple cell metabolism and stress granule disassembly
por: Cereghetti, Gea, et al.
Publicado: (2021) -
Different Heat Shock Proteins Bind α-Synuclein With Distinct Mechanisms and Synergistically Prevent Its Amyloid Aggregation
por: Jia, Chunyu, et al.
Publicado: (2019) -
Amyloid assembly and disassembly
por: Chuang, Edward, et al.
Publicado: (2018)