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In vivo imaging of microenvironmental and anti-PD-L1-mediated dynamics in cancer using S100A8/S100A9 as an imaging biomarker
Purpose: As a promotor of tumor invasion and tumor microenvironment (TME) formation, the protein complex S100A8/S100A9 is associated with poor prognosis. Our aim was to further evaluate its origin and regulatory effects, and to establish an imaging biomarker for TME activity. Methods: S100A9(−/−)cel...
Autores principales: | Helfen, Anne, Rieß, Jan, Fehler, Olesja, Stölting, Miriam, An, Zhengwen, Kocman, Vanessa, Schnepel, Annika, Geyer, Christiane, Gerwing, Mirjam, Masthoff, Max, Vogl, Thomas, Höltke, Carsten, Roth, Johannes, Ng, Tony, Wildgruber, Moritz, Eisenblätter, Michel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983428/ https://www.ncbi.nlm.nih.gov/pubmed/35367789 http://dx.doi.org/10.1016/j.neo.2022.100792 |
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