CD19/BAFF-R dual targeted CAR T cells for treatment of mixed antigen-negative variants of acute lymphoblastic leukemia

Chimeric antigen receptor (CAR) T cells targeting CD19 mediate potent anti-tumor effects in B cell malignancies including acute lymphoblastic leukemia (ALL), but antigen loss remains the major cause of treatment failure. To mitigate antigen escape and potentially improve durability of remission, we...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Xiuli, Dong, Zhenyuan, Awuah, Dennis, Chang, Wen-Chung, Cheng, Wesley A, Vyas, Vibhuti, Cha, Soungchul, Anderson, Aaron, Zhang, Tiantian, Wang, Zhe, Szymura, Szymon, Kuang, Benjamin, Clark, Mary C., Aldoss, Ibrahim, Forman, Stephen J., Kwak, Larry W, Qin, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983465/
https://www.ncbi.nlm.nih.gov/pubmed/35039637
http://dx.doi.org/10.1038/s41375-021-01477-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983465/
https://www.ncbi.nlm.nih.gov/pubmed/35039637
http://dx.doi.org/10.1038/s41375-021-01477-x

Ejemplares similares