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CD19/BAFF-R dual targeted CAR T cells for treatment of mixed antigen-negative variants of acute lymphoblastic leukemia

Chimeric antigen receptor (CAR) T cells targeting CD19 mediate potent anti-tumor effects in B cell malignancies including acute lymphoblastic leukemia (ALL), but antigen loss remains the major cause of treatment failure. To mitigate antigen escape and potentially improve durability of remission, we...

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Detalles Bibliográficos
Autores principales:	Wang, Xiuli, Dong, Zhenyuan, Awuah, Dennis, Chang, Wen-Chung, Cheng, Wesley A, Vyas, Vibhuti, Cha, Soungchul, Anderson, Aaron, Zhang, Tiantian, Wang, Zhe, Szymura, Szymon, Kuang, Benjamin, Clark, Mary C., Aldoss, Ibrahim, Forman, Stephen J., Kwak, Larry W, Qin, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983465/ https://www.ncbi.nlm.nih.gov/pubmed/35039637 http://dx.doi.org/10.1038/s41375-021-01477-x

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