MUC1-C Dictates JUN and BAF-Mediated Chromatin Remodeling at Enhancer Signatures in Cancer Stem Cells

The oncogenic MUC1-C protein promotes dedifferentiation of castrate-resistant prostate cancer (CRPC) and triple-negative breast cancer (TNBC) cells. Chromatin remodeling is critical for the cancer stem cell (CSC) state; however, there is no definitive evidence that MUC1-C regulates chromatin accessi...

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Detalles Bibliográficos
Autores principales: Bhattacharya, Atrayee, Fushimi, Atsushi, Yamashita, Nami, Hagiwara, Masayuki, Morimoto, Yoshihiro, Rajabi, Hasan, Long, Mark D., Abdulla, Maha, Ahmad, Rehan, Street, Kelly, Liu, Song, Liu, Tao, Kufe, Donald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Cancer “-Omics”
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983489/
https://www.ncbi.nlm.nih.gov/pubmed/35022313
http://dx.doi.org/10.1158/1541-7786.MCR-21-0672

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983489/
https://www.ncbi.nlm.nih.gov/pubmed/35022313
http://dx.doi.org/10.1158/1541-7786.MCR-21-0672

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