Triple-negative breast carcinomas of low malignant potential: review on diagnostic criteria and differential diagnoses

Triple-negative breast carcinomas constitute a wide spectrum of lesions, mostly being highly aggressive. Nevertheless, some special histologic subtypes can have low malignant potential. The purpose of the present paper is to review diagnostic criteria and prognostic parameters of breast neoplasms of...

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Detalles Bibliográficos
Autores principales: Cima, L., Kaya, H., Marchiò, C., Nishimura, R., Wen, H. Y., Fabbri, V. P., Foschini, M. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983547/
https://www.ncbi.nlm.nih.gov/pubmed/34458945
http://dx.doi.org/10.1007/s00428-021-03174-7
Descripción
Sumario:Triple-negative breast carcinomas constitute a wide spectrum of lesions, mostly being highly aggressive. Nevertheless, some special histologic subtypes can have low malignant potential. The purpose of the present paper is to review diagnostic criteria and prognostic parameters of breast neoplasms of special histotypes. Specifically, adenoid cystic carcinoma, adenomyoepithelioma, acinic cell carcinoma, mucoepidermoid carcinoma, tall cell carcinoma with reverse polarity, and secretory carcinoma will be discussed. For each tumour, definition and morphological and molecular features, together with prognostic parameters, will be presented. Paradigmatic cases will be illustrated. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00428-021-03174-7.

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