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Integrative analysis of non-small cell lung cancer patient-derived xenografts identifies distinct proteotypes associated with patient outcomes

Non-small cell lung cancer (NSCLC) is the leading cause of cancer deaths worldwide. Only a fraction of NSCLC harbor actionable driver mutations and there is an urgent need for patient-derived model systems that will enable the development of new targeted therapies. NSCLC and other cancers display pr...

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Detalles Bibliográficos
Autores principales: Mirhadi, Shideh, Tam, Shirley, Li, Quan, Moghal, Nadeem, Pham, Nhu-An, Tong, Jiefei, Golbourn, Brian J., Krieger, Jonathan R., Taylor, Paul, Li, Ming, Weiss, Jessica, Martins-Filho, Sebastiao N., Raghavan, Vibha, Mamatjan, Yasin, Khan, Aafaque A., Cabanero, Michael, Sakashita, Shingo, Huo, Kugeng, Agnihotri, Sameer, Ishizawa, Kota, Waddell, Thomas K., Zadeh, Gelareh, Yasufuku, Kazuhiro, Liu, Geoffrey, Shepherd, Frances A., Moran, Michael F., Tsao, Ming-Sound
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983714/
https://www.ncbi.nlm.nih.gov/pubmed/35383171
http://dx.doi.org/10.1038/s41467-022-29444-9