RNA aptamers specific for transmembrane p24 trafficking protein 6 and Clusterin for the targeted delivery of imaging reagents and RNA therapeutics to human β cells

The ability to detect and target β cells in vivo can substantially refine how diabetes is studied and treated. However, the lack of specific probes still hampers a precise characterization of human β cell mass and the delivery of therapeutics in clinical settings. Here, we report the identification...

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Detalles Bibliográficos
Autores principales: Van Simaeys, Dimitri, De La Fuente, Adriana, Zilio, Serena, Zoso, Alessia, Kuznetsova, Victoria, Alcazar, Oscar, Buchwald, Peter, Grilli, Andrea, Caroli, Jimmy, Bicciato, Silvio, Serafini, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983715/
https://www.ncbi.nlm.nih.gov/pubmed/35383192
http://dx.doi.org/10.1038/s41467-022-29377-3