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Incidence of preterm premature rupture of membranes and its association with inter-pregnancy interval: a prospective cohort study

Preterm premature rupture of membranes is one of the causes of premature birth and perinatal deaths, particularly in developing countries due to poor access and availability of medical resources to manage and sustain the pregnancy to term. Although, several risk factors for preterm premature rupture...

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Autores principales: Jena, Belayneh Hamdela, Biks, Gashaw Andargie, Gete, Yigzaw Kebede, Gelaye, Kassahun Alemu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983720/
https://www.ncbi.nlm.nih.gov/pubmed/35383259
http://dx.doi.org/10.1038/s41598-022-09743-3
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author Jena, Belayneh Hamdela
Biks, Gashaw Andargie
Gete, Yigzaw Kebede
Gelaye, Kassahun Alemu
author_facet Jena, Belayneh Hamdela
Biks, Gashaw Andargie
Gete, Yigzaw Kebede
Gelaye, Kassahun Alemu
author_sort Jena, Belayneh Hamdela
collection PubMed
description Preterm premature rupture of membranes is one of the causes of premature birth and perinatal deaths, particularly in developing countries due to poor access and availability of medical resources to manage and sustain the pregnancy to term. Although, several risk factors for preterm premature rupture of membranes were identified, its association with inter-pregnancy interval was understudied. Therefore, we aimed to assess the incidence of preterm premature rupture of membranes and its association with inter-pregnancy interval in urban South Ethiopia. A community-based prospective cohort study was conducted among 2578 pregnant women, and followed until delivery. A generalized linear model for binary outcome was applied for the analysis, using a 95% confidence level and P-value. The incidence of preterm premature rupture of membranes was 2%, 95% CI: 2%, 3%. However, the incidence was varied across the months of inter-pregnancy intervals 4% (< 18 months), 2% (18–23 months) and 1% (24–60 months). The risk of preterm premature rupture of membranes was nearly three times (ARR = 2.59, 95%CI: 1.27, 5.29) higher for women with inter-pregnancy intervals < 18 months than 24–60 months. Inter-pregnancy interval under 18 months increases the risk of preterm premature rupture of membranes, highlighting the need to improve pregnancy spacing in the community.
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spelling pubmed-89837202022-04-06 Incidence of preterm premature rupture of membranes and its association with inter-pregnancy interval: a prospective cohort study Jena, Belayneh Hamdela Biks, Gashaw Andargie Gete, Yigzaw Kebede Gelaye, Kassahun Alemu Sci Rep Article Preterm premature rupture of membranes is one of the causes of premature birth and perinatal deaths, particularly in developing countries due to poor access and availability of medical resources to manage and sustain the pregnancy to term. Although, several risk factors for preterm premature rupture of membranes were identified, its association with inter-pregnancy interval was understudied. Therefore, we aimed to assess the incidence of preterm premature rupture of membranes and its association with inter-pregnancy interval in urban South Ethiopia. A community-based prospective cohort study was conducted among 2578 pregnant women, and followed until delivery. A generalized linear model for binary outcome was applied for the analysis, using a 95% confidence level and P-value. The incidence of preterm premature rupture of membranes was 2%, 95% CI: 2%, 3%. However, the incidence was varied across the months of inter-pregnancy intervals 4% (< 18 months), 2% (18–23 months) and 1% (24–60 months). The risk of preterm premature rupture of membranes was nearly three times (ARR = 2.59, 95%CI: 1.27, 5.29) higher for women with inter-pregnancy intervals < 18 months than 24–60 months. Inter-pregnancy interval under 18 months increases the risk of preterm premature rupture of membranes, highlighting the need to improve pregnancy spacing in the community. Nature Publishing Group UK 2022-04-05 /pmc/articles/PMC8983720/ /pubmed/35383259 http://dx.doi.org/10.1038/s41598-022-09743-3 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Jena, Belayneh Hamdela
Biks, Gashaw Andargie
Gete, Yigzaw Kebede
Gelaye, Kassahun Alemu
Incidence of preterm premature rupture of membranes and its association with inter-pregnancy interval: a prospective cohort study
title Incidence of preterm premature rupture of membranes and its association with inter-pregnancy interval: a prospective cohort study
title_full Incidence of preterm premature rupture of membranes and its association with inter-pregnancy interval: a prospective cohort study
title_fullStr Incidence of preterm premature rupture of membranes and its association with inter-pregnancy interval: a prospective cohort study
title_full_unstemmed Incidence of preterm premature rupture of membranes and its association with inter-pregnancy interval: a prospective cohort study
title_short Incidence of preterm premature rupture of membranes and its association with inter-pregnancy interval: a prospective cohort study
title_sort incidence of preterm premature rupture of membranes and its association with inter-pregnancy interval: a prospective cohort study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983720/
https://www.ncbi.nlm.nih.gov/pubmed/35383259
http://dx.doi.org/10.1038/s41598-022-09743-3
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