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Structural basis for the SUMO protease activity of the atypical ubiquitin-specific protease USPL1

Post-translational protein modifications by ubiquitin and ubiquitin-like modifiers regulate many major pathways in the cell. These modifications can be reversed by de-ubiquitinating enzymes such as ubiquitin-specific proteases (USPs). Proteolytic activity towards ubiquitin-modified substrates is com...

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Detalles Bibliográficos
Autores principales: Li, Ying, Varejão, Nathalia, Reverter, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983731/
https://www.ncbi.nlm.nih.gov/pubmed/35383180
http://dx.doi.org/10.1038/s41467-022-29485-0

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