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Risk factors for undergoing surgery in patients with newly diagnosed open-angle glaucoma
Despite the clinical importance of glaucoma surgery, studies on its prevalence and risk factors are limited. We analyzed a database comprising approximately 1,000,000 Korean residents to investigate the prevalence and risk factors for undergoing glaucoma surgery within 5 years of diagnosis with open...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983768/ https://www.ncbi.nlm.nih.gov/pubmed/35383265 http://dx.doi.org/10.1038/s41598-022-09832-3 |
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author | Lee, Seung Jae Lee, Sang Ah Lee, Seungyeon Bae, Hyoung Won Kim, Chan Yun Seong, Gong Je Park, Jong Woon Lee, Kwanghyun |
author_facet | Lee, Seung Jae Lee, Sang Ah Lee, Seungyeon Bae, Hyoung Won Kim, Chan Yun Seong, Gong Je Park, Jong Woon Lee, Kwanghyun |
author_sort | Lee, Seung Jae |
collection | PubMed |
description | Despite the clinical importance of glaucoma surgery, studies on its prevalence and risk factors are limited. We analyzed a database comprising approximately 1,000,000 Korean residents to investigate the prevalence and risk factors for undergoing glaucoma surgery within 5 years of diagnosis with open-angle glaucoma. Of the 4,303 patients evaluated, 226 (5.3%) underwent glaucoma surgery. Factors associated with the likelihood of glaucoma surgery included the use of two or more eye drops (odds ratio [OR], 30.30; 95% confidence interval [CI], 10.95–83.84), intake of oral carbonic anhydrase inhibitor (OR, 1.79; 95% CI, 1.23–2.61), age > 55 years (55–65 years: OR, 1.71; 95% CI, 1.06–2.76; > 65 years: OR 1.72; 95% CI, 1.10–2.70), female sex (OR, 1.46; 95% CI, 1.10–1.94), middle- and high-income (OR, 2.36; 95% CI, 1.30–4.28, OR, 1.86; 95% CI, 1.03–3.35, respectively), and metropolitan residence (OR, 1.61; 95% CI, 1.14–2.26). Our nomogram for predicting the likelihood of glaucoma surgery showed an acceptable result. In conclusion, older age, female sex, and the intensity of intraocular pressure lowering treatment increased the likelihood of undergoing glaucoma surgery. Our findings indicated that a lower socioeconomic status may forestall receiving this necessary surgery, which requires further attention. |
format | Online Article Text |
id | pubmed-8983768 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-89837682022-04-06 Risk factors for undergoing surgery in patients with newly diagnosed open-angle glaucoma Lee, Seung Jae Lee, Sang Ah Lee, Seungyeon Bae, Hyoung Won Kim, Chan Yun Seong, Gong Je Park, Jong Woon Lee, Kwanghyun Sci Rep Article Despite the clinical importance of glaucoma surgery, studies on its prevalence and risk factors are limited. We analyzed a database comprising approximately 1,000,000 Korean residents to investigate the prevalence and risk factors for undergoing glaucoma surgery within 5 years of diagnosis with open-angle glaucoma. Of the 4,303 patients evaluated, 226 (5.3%) underwent glaucoma surgery. Factors associated with the likelihood of glaucoma surgery included the use of two or more eye drops (odds ratio [OR], 30.30; 95% confidence interval [CI], 10.95–83.84), intake of oral carbonic anhydrase inhibitor (OR, 1.79; 95% CI, 1.23–2.61), age > 55 years (55–65 years: OR, 1.71; 95% CI, 1.06–2.76; > 65 years: OR 1.72; 95% CI, 1.10–2.70), female sex (OR, 1.46; 95% CI, 1.10–1.94), middle- and high-income (OR, 2.36; 95% CI, 1.30–4.28, OR, 1.86; 95% CI, 1.03–3.35, respectively), and metropolitan residence (OR, 1.61; 95% CI, 1.14–2.26). Our nomogram for predicting the likelihood of glaucoma surgery showed an acceptable result. In conclusion, older age, female sex, and the intensity of intraocular pressure lowering treatment increased the likelihood of undergoing glaucoma surgery. Our findings indicated that a lower socioeconomic status may forestall receiving this necessary surgery, which requires further attention. Nature Publishing Group UK 2022-04-05 /pmc/articles/PMC8983768/ /pubmed/35383265 http://dx.doi.org/10.1038/s41598-022-09832-3 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Lee, Seung Jae Lee, Sang Ah Lee, Seungyeon Bae, Hyoung Won Kim, Chan Yun Seong, Gong Je Park, Jong Woon Lee, Kwanghyun Risk factors for undergoing surgery in patients with newly diagnosed open-angle glaucoma |
title | Risk factors for undergoing surgery in patients with newly diagnosed open-angle glaucoma |
title_full | Risk factors for undergoing surgery in patients with newly diagnosed open-angle glaucoma |
title_fullStr | Risk factors for undergoing surgery in patients with newly diagnosed open-angle glaucoma |
title_full_unstemmed | Risk factors for undergoing surgery in patients with newly diagnosed open-angle glaucoma |
title_short | Risk factors for undergoing surgery in patients with newly diagnosed open-angle glaucoma |
title_sort | risk factors for undergoing surgery in patients with newly diagnosed open-angle glaucoma |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983768/ https://www.ncbi.nlm.nih.gov/pubmed/35383265 http://dx.doi.org/10.1038/s41598-022-09832-3 |
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