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Risk factors for undergoing surgery in patients with newly diagnosed open-angle glaucoma

Despite the clinical importance of glaucoma surgery, studies on its prevalence and risk factors are limited. We analyzed a database comprising approximately 1,000,000 Korean residents to investigate the prevalence and risk factors for undergoing glaucoma surgery within 5 years of diagnosis with open...

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Autores principales: Lee, Seung Jae, Lee, Sang Ah, Lee, Seungyeon, Bae, Hyoung Won, Kim, Chan Yun, Seong, Gong Je, Park, Jong Woon, Lee, Kwanghyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983768/
https://www.ncbi.nlm.nih.gov/pubmed/35383265
http://dx.doi.org/10.1038/s41598-022-09832-3
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author Lee, Seung Jae
Lee, Sang Ah
Lee, Seungyeon
Bae, Hyoung Won
Kim, Chan Yun
Seong, Gong Je
Park, Jong Woon
Lee, Kwanghyun
author_facet Lee, Seung Jae
Lee, Sang Ah
Lee, Seungyeon
Bae, Hyoung Won
Kim, Chan Yun
Seong, Gong Je
Park, Jong Woon
Lee, Kwanghyun
author_sort Lee, Seung Jae
collection PubMed
description Despite the clinical importance of glaucoma surgery, studies on its prevalence and risk factors are limited. We analyzed a database comprising approximately 1,000,000 Korean residents to investigate the prevalence and risk factors for undergoing glaucoma surgery within 5 years of diagnosis with open-angle glaucoma. Of the 4,303 patients evaluated, 226 (5.3%) underwent glaucoma surgery. Factors associated with the likelihood of glaucoma surgery included the use of two or more eye drops (odds ratio [OR], 30.30; 95% confidence interval [CI], 10.95–83.84), intake of oral carbonic anhydrase inhibitor (OR, 1.79; 95% CI, 1.23–2.61), age > 55 years (55–65 years: OR, 1.71; 95% CI, 1.06–2.76; > 65 years: OR 1.72; 95% CI, 1.10–2.70), female sex (OR, 1.46; 95% CI, 1.10–1.94), middle- and high-income (OR, 2.36; 95% CI, 1.30–4.28, OR, 1.86; 95% CI, 1.03–3.35, respectively), and metropolitan residence (OR, 1.61; 95% CI, 1.14–2.26). Our nomogram for predicting the likelihood of glaucoma surgery showed an acceptable result. In conclusion, older age, female sex, and the intensity of intraocular pressure lowering treatment increased the likelihood of undergoing glaucoma surgery. Our findings indicated that a lower socioeconomic status may forestall receiving this necessary surgery, which requires further attention.
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spelling pubmed-89837682022-04-06 Risk factors for undergoing surgery in patients with newly diagnosed open-angle glaucoma Lee, Seung Jae Lee, Sang Ah Lee, Seungyeon Bae, Hyoung Won Kim, Chan Yun Seong, Gong Je Park, Jong Woon Lee, Kwanghyun Sci Rep Article Despite the clinical importance of glaucoma surgery, studies on its prevalence and risk factors are limited. We analyzed a database comprising approximately 1,000,000 Korean residents to investigate the prevalence and risk factors for undergoing glaucoma surgery within 5 years of diagnosis with open-angle glaucoma. Of the 4,303 patients evaluated, 226 (5.3%) underwent glaucoma surgery. Factors associated with the likelihood of glaucoma surgery included the use of two or more eye drops (odds ratio [OR], 30.30; 95% confidence interval [CI], 10.95–83.84), intake of oral carbonic anhydrase inhibitor (OR, 1.79; 95% CI, 1.23–2.61), age > 55 years (55–65 years: OR, 1.71; 95% CI, 1.06–2.76; > 65 years: OR 1.72; 95% CI, 1.10–2.70), female sex (OR, 1.46; 95% CI, 1.10–1.94), middle- and high-income (OR, 2.36; 95% CI, 1.30–4.28, OR, 1.86; 95% CI, 1.03–3.35, respectively), and metropolitan residence (OR, 1.61; 95% CI, 1.14–2.26). Our nomogram for predicting the likelihood of glaucoma surgery showed an acceptable result. In conclusion, older age, female sex, and the intensity of intraocular pressure lowering treatment increased the likelihood of undergoing glaucoma surgery. Our findings indicated that a lower socioeconomic status may forestall receiving this necessary surgery, which requires further attention. Nature Publishing Group UK 2022-04-05 /pmc/articles/PMC8983768/ /pubmed/35383265 http://dx.doi.org/10.1038/s41598-022-09832-3 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Lee, Seung Jae
Lee, Sang Ah
Lee, Seungyeon
Bae, Hyoung Won
Kim, Chan Yun
Seong, Gong Je
Park, Jong Woon
Lee, Kwanghyun
Risk factors for undergoing surgery in patients with newly diagnosed open-angle glaucoma
title Risk factors for undergoing surgery in patients with newly diagnosed open-angle glaucoma
title_full Risk factors for undergoing surgery in patients with newly diagnosed open-angle glaucoma
title_fullStr Risk factors for undergoing surgery in patients with newly diagnosed open-angle glaucoma
title_full_unstemmed Risk factors for undergoing surgery in patients with newly diagnosed open-angle glaucoma
title_short Risk factors for undergoing surgery in patients with newly diagnosed open-angle glaucoma
title_sort risk factors for undergoing surgery in patients with newly diagnosed open-angle glaucoma
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983768/
https://www.ncbi.nlm.nih.gov/pubmed/35383265
http://dx.doi.org/10.1038/s41598-022-09832-3
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