ACKR3 regulates platelet activation and ischemia-reperfusion tissue injury

Platelet activation plays a critical role in thrombosis. Inhibition of platelet activation is a cornerstone in treatment of acute organ ischemia. Platelet ACKR3 surface expression is independently associated with all-cause mortality in CAD patients. In a novel genetic mouse strain, we show that mega...

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Detalles Bibliográficos
Autores principales: Rohlfing, Anne-Katrin, Kolb, Kyra, Sigle, Manuel, Ziegler, Melanie, Bild, Alexander, Münzer, Patrick, Sudmann, Jessica, Dicenta, Valerie, Harm, Tobias, Manke, Mailin-Christin, Geue, Sascha, Kremser, Marcel, Chatterjee, Madhumita, Liang, Chunguang, von Eysmondt, Hendrik, Dandekar, Thomas, Heinzmann, David, Günter, Manina, von Ungern-Sternberg, Saskia, Büttcher, Manuela, Castor, Tatsiana, Mencl, Stine, Langhauser, Friederike, Sies, Katharina, Ashour, Diyaa, Beker, Mustafa Caglar, Lämmerhofer, Michael, Autenrieth, Stella E., Schäffer, Tilman E., Laufer, Stefan, Szklanna, Paulina, Maguire, Patricia, Heikenwalder, Matthias, Müller, Karin Anne Lydia, Hermann, Dirk M., Kilic, Ertugrul, Stumm, Ralf, Ramos, Gustavo, Kleinschnitz, Christoph, Borst, Oliver, Langer, Harald F., Rath, Dominik, Gawaz, Meinrad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983782/
https://www.ncbi.nlm.nih.gov/pubmed/35383158
http://dx.doi.org/10.1038/s41467-022-29341-1

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