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Assessment of hyperprogression versus the natural course of disease development with nivolumab with or without ipilimumab versus placebo in phase III, randomized, controlled trials
BACKGROUND: Retrospective studies have suggested a potential risk of hyperprogressive disease (HPD) in patients receiving immune checkpoint inhibitors (ICIs). We compared the incidence of HPD during treatment with nivolumab±ipilimumab versus natural tumor progression with placebo in post hoc analyse...
Autores principales: | Kang, Yoon-Koo, Reck, Martin, Nghiem, Paul, Feng, Yan, Plautz, Gregory, Kim, Hye Ryun, Owonikoko, Taofeek K, Boku, Narikazu, Chen, Li-Tzong, Lei, Ming, Chang, Han, Lin, Wen Hong, Roy, Amit, Bello, Akintunde, Sheng, Jennifer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983994/ https://www.ncbi.nlm.nih.gov/pubmed/35383114 http://dx.doi.org/10.1136/jitc-2021-004273 |
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