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Subtyping of microsatellite stability colorectal cancer reveals guanylate binding protein 2 (GBP2) as a potential immunotherapeutic target

BACKGROUNDS: Proficient-mismatch-repair or microsatellite stability (pMMR/MSS) colorectal cancer (CRC) has limited efficacy for immune checkpoint blockade (ICB) therapy and its underlying mechanism remains unclear. Guanylate binding protein 2 (GBP2) is a member of the GTPase family and is crucial to...

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Detalles Bibliográficos
Autores principales:	Wang, Haizhou, Zhou, Yabo, Zhang, Yangyang, Fang, Shilin, Zhang, Meng, Li, Haiou, Xu, Fei, Liu, Lan, Liu, Jing, Zhao, Qiu, Wang, Fan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2022
Materias:	Immunotherapy Biomarkers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8984016/ https://www.ncbi.nlm.nih.gov/pubmed/35383115 http://dx.doi.org/10.1136/jitc-2021-004302

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