Cargando…

Shexiang Tongxin Dropping Pills Promote Macrophage Polarization-Induced Angiogenesis Against Coronary Microvascular Dysfunction via PI3K/Akt/mTORC1 Pathway

Background: Accumulating evidence suggests that coronary microvascular dysfunction (CMD) is one of the important causes of coronary artery diseases. Angiogenesis can effectively improve CMD by increasing blood supply capacity, recovering cardiac function and poor hemodynamics. Clinical studies have...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lu, Xiangyu, Yao, Junkai, Li, Changxiang, Cui, Lingwen, Liu, Yizhou, Liu, Xiangning, Wang, Gang, Dong, Jianteng, Deng, Qiong, Hu, Yueyao, Guo, Dongqing, Wang, Wei, Li, Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8984141/ https://www.ncbi.nlm.nih.gov/pubmed/35401214 http://dx.doi.org/10.3389/fphar.2022.840521

Ejemplares similares

Shexiang Tongxin Dropping Pill Improves Peripheral Microvascular Blood Flow via Cystathionine-γ-Lyase
por: Zhang, Yanda, et al.
Publicado: (2019)

Exploring the mechanism of Shexiang Tongxin dropping pill in the treatment of microvascular angina through network pharmacology and molecular docking
por: Chang, Chen, et al.
Publicado: (2022)

Efficacy of Shexiang Tongxin Dropping Pills in a Swine Model of Coronary Slow Flow
por: Bai, Yupeng, et al.
Publicado: (2022)

Shexiang Tongxin dropping pill protects against isoproterenol-induced myocardial ischemia in vivo and in vitro
por: Qi, Jianyong, et al.
Publicado: (2017)

Protective effects of Shexiang Tongxin Dropping Pill on pituitrin-induced acute myocardial ischemia in rats
por: Lin, Shan, et al.
Publicado: (2017)

Effect of Shexiang Tongxin dropping pill on stable coronary artery disease patients with normal fractional flow reserve and coronary microvascular disease: A study protocol
por: Lu, Yanli, et al.
Publicado: (2020)

Shexiang Tongxin Dropping Pill Protects Against Chronic Heart Failure in Mice via Inhibiting the ERK/MAPK and TGF-β Signaling Pathways
por: Zhang, Shuying, et al.
Publicado: (2021)

Qualitative and Quantitative Analysis of the Major Constituents in Shexiang Tongxin Dropping Pill by HPLC-Q-TOF-MS/MS and UPLC-QqQ-MS/MS
por: Chen, Daxin, et al.
Publicado: (2015)

Effect of Musk Tongxin Dropping Pill on Myocardial Remodeling and Microcirculation Dysfunction in Diabetic Cardiomyopathy
por: Zhao, Jingjing, et al.
Publicado: (2021)

The effect of Shexiang Tongxin Dropping Pills on coronary microvascular dysfunction (CMVD) among those with a mental disorder and non-obstructive coronary artery disease based on stress cardiac magnetic resonance images: A study protocol
por: Tian, Jinfan, et al.
Publicado: (2020)

Effects of Shexiang Baoxin Pill for Coronary Microvascular Function: A Systematic Review and Meta-Analysis
por: Wang, Mengxi, et al.
Publicado: (2021)

Protective Effect of Shexiang Baoxin Pill on Myocardial Ischemia/Reperfusion Injury in Patients With STEMI
por: Qin, Haixia, et al.
Publicado: (2021)

Shexiang Baoxin Pills for Coronary Heart Disease in Animal Models: Preclinical Evidence and Promoting Angiogenesis Mechanism
por: Zhang, Ke-Jian, et al.
Publicado: (2017)

A network-based method for mechanistic investigation of Shexiang Baoxin Pill’s treatment of cardiovascular diseases
por: Fang, Hai-Yang, et al.
Publicado: (2017)

Meta-analysis and trial sequential analysis of shexiang baoxin pill for coronary slow flow
por: Guo, Hongxin, et al.
Publicado: (2022)

Metabolomic Strategy for Studying the Intervention and the Synergistic Effects of the Shexiang Baoxin Pill for Treating Myocardial Infarction in Rats
por: Xiang, Li, et al.
Publicado: (2013)

Musk Tongxin Dripping Pills for treating Ticagrelor in Patients After Percutaneous Coronary Intervention: Echocardiography Combined with Untargeted Metabolomics
por: Nan, Lyu, et al.
Publicado: (2021)

Shexiang Baoxin Pill Alleviates the Atherosclerotic Lesions in Mice via Improving Inflammation Response and Inhibiting Lipid Accumulation in the Arterial Wall
por: Lu, Li, et al.
Publicado: (2019)

Both mTORC1 and mTORC2 are involved in the regulation of cell adhesion
por: Chen, Long, et al.
Publicado: (2015)

Co-administration of Shexiang Baoxin Pill and Chemotherapy Drugs Potentiated Cancer Therapy by Vascular-Promoting Strategy
por: Yang, Liu-qing, et al.
Publicado: (2019)

Shexiang Baoxin Pill for Acute Myocardial Infarction: Clinical Evidence and Molecular Mechanism of Antioxidative Stress
por: Guo, Jianbo, et al.
Publicado: (2021)

mTORC1 and mTORC2 in cancer and the tumor microenvironment
por: Kim, Laura C., et al.
Publicado: (2016)

Pathogenic Role of mTORC1 and mTORC2 in Pulmonary Hypertension
por: Tang, Haiyang, et al.
Publicado: (2018)

Shexiang Baoxin Pill Corrects Metabolic Disorders in a Rat Model of Metabolic Syndrome by Targeting Mitochondria
por: Wei, Dan, et al.
Publicado: (2018)

Shexiang Baoxin Pills as an Adjuvant Treatment for Chronic Heart Failure: A System Review and Meta-Analysis
por: Dong, Taiwei, et al.
Publicado: (2018)

Efficacy of Shexiang Baoxin Pills for the treatment of unstable angina pectoris: Protocol of systemic review and meta-analysis
por: Chen, Huadong, et al.
Publicado: (2019)

LC-MS-based metabolomics reveals the mechanism of anti-gouty arthritis effect of Wuwei Shexiang pill
por: Lang, Jirui, et al.
Publicado: (2023)

Rapamycin inhibits mSin1 phosphorylation independently of mTORC1 and mTORC2
por: Luo, Yan, et al.
Publicado: (2015)

Exploring the active ingredients and mechanism of Shenzhi Tongxin capsule against microvascular angina based on network pharmacology and molecular docking
por: Xuan, Xiaoyu, et al.
Publicado: (2023)

The metabolic waste ammonium regulates mTORC2 and mTORC1 signaling
por: Merhi, Ahmad, et al.
Publicado: (2017)

mTORC1-Mediated Angiogenesis is Required for the Development of Rosacea
por: Peng, Qinqin, et al.
Publicado: (2021)

Shexiang-Wulong Pills Attenuate Rheumatoid Arthritis by Alleviating Inflammation in a Mouse Model of Collagen-Induced Arthritis
por: Zhang, Zhihui, et al.
Publicado: (2019)

Shexiang Baoxin Pill, Derived From the Traditional Chinese Medicine, Provides Protective Roles Against Cardiovascular Diseases
por: Lu, Li, et al.
Publicado: (2018)

Antidepressant and anxiolytic effects of the proprietary Chinese medicine Shexiang Baoxin pill in mice with chronic unpredictable mild stress
por: Zhou, Xi-Dan, et al.
Publicado: (2018)

Mechanism Investigation of Wuwei Shexiang Pills on Gouty Arthritis via Network Pharmacology, Molecule Docking, and Pharmacological Verification
por: Lang, Jirui, et al.
Publicado: (2022)

mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation
por: Ding, Xiaolei, et al.
Publicado: (2016)

LPS Induces mTORC1 and mTORC2 Activation During Monocyte Adhesion
por: Ribeiro, Marcelle C., et al.
Publicado: (2018)

mTORC1 and mTORC2 differentially promote natural killer cell development
por: Yang, Chao, et al.
Publicado: (2018)

mTORC1 and mTORC2 are differentially engaged in the development of laser-induced CNV
por: Yang, Jin Young, et al.
Publicado: (2019)

Dopamine neuron morphology and output are differentially controlled by mTORC1 and mTORC2
por: Kosillo, Polina, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_hdqnd3d60d7p20g26oh9g92ba9