Proteomic and Single-Cell Transcriptomic Dissection of Human Plasmacytoid Dendritic Cell Response to Influenza Virus

Plasmacytoid dendritic cells [pDCs] represent a rare innate immune subset uniquely endowed with the capacity to produce substantial amounts of type-I interferons. This function of pDCs is critical for effective antiviral defenses and has been implicated in autoimmunity. While IFN-I and select cytoki...

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Detalles Bibliográficos
Autores principales: Ghanem, Mustafa H., Shih, Andrew J., Khalili, Houman, Werth, Emily G., Chakrabarty, Jayanta K., Brown, Lewis M., Simpfendorfer, Kim R., Gregersen, Peter K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8984281/
https://www.ncbi.nlm.nih.gov/pubmed/35401570
http://dx.doi.org/10.3389/fimmu.2022.814627

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