Cargando…

Multi-scale modelling reveals that early super-spreader events are a likely contributor to novel variant predominance

The emergence of new SARS-CoV-2 variants of concern (VOC) has hampered international efforts to contain the COVID-19 pandemic. VOCs have been characterized to varying degrees by higher transmissibility, worse infection outcomes and evasion of vaccine and infection-induced immunologic memory. VOCs ar...

Descripción completa

Detalles Bibliográficos
Autores principales:	Goyal, Ashish, Reeves, Daniel B., Schiffer, Joshua T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society 2022
Materias:	Life Sciences–Mathematics interface
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8984334/ https://www.ncbi.nlm.nih.gov/pubmed/35382576 http://dx.doi.org/10.1098/rsif.2021.0811

Ejemplares similares

Timing HIV infection with a simple and accurate population viral dynamics model
por: Reeves, Daniel B., et al.
Publicado: (2021)

A multi-scale model explains oscillatory slowing and neuronal hyperactivity in Alzheimer’s disease
por: Alexandersen, Christoffer G., et al.
Publicado: (2023)

Multi-scale mechanistic modelling of the host defence in invasive aspergillosis reveals leucocyte activation and iron acquisition as drivers of infection outcome
por: Ribeiro, Henrique AL, et al.
Publicado: (2022)

The importance of the generation interval in investigating dynamics and control of new SARS-CoV-2 variants
por: Park, Sang Woo, et al.
Publicado: (2022)

Urban scaling in Europe
por: Bettencourt, Luís M. A., et al.
Publicado: (2016)

Sub-spreading events limit the reliable elimination of heterogeneous epidemics
por: Parag, Kris V.
Publicado: (2021)

Urban geography and scaling of contemporary Indian cities
por: Sahasranaman, Anand, et al.
Publicado: (2019)

How the geometry of cities determines urban scaling laws
por: Molinero, Carlos, et al.
Publicado: (2021)

Multi-rhythmicity generated by coupling two cellular rhythms
por: Yan, Jie, et al.
Publicado: (2019)

Multi-level combinatoriality in magpie non-song vocalizations
por: Walsh, Sarah L., et al.
Publicado: (2023)

Connecting empirical phenomena and theoretical models of biological coordination across scales
por: Zhang, Mengsen, et al.
Publicado: (2019)

A multi-layer model for the early detection of COVID-19
por: Shmueli, Erez, et al.
Publicado: (2021)

Super-spreaders in infectious diseases
por: Stein, Richard A.
Publicado: (2011)

Core signalling motif displaying multistability through multi-state enzymes
por: Feng, Song, et al.
Publicado: (2016)

Multi-model and network inference based on ensemble estimates: avoiding the madness of crowds
por: Stumpf, Michael P. H.
Publicado: (2020)

The three-dimensional coarse-graining formulation of interacting elastohydrodynamic filaments and multi-body microhydrodynamics
por: Fuchter, Paul, et al.
Publicado: (2023)

COVID-19 pandemic dynamics in India, the SARS-CoV-2 Delta variant and implications for vaccination
por: Yang, Wan, et al.
Publicado: (2022)

Modelling the viral dynamics of the SARS-CoV-2 Delta and Omicron variants in different cell types
por: McCormack, Clare P., et al.
Publicado: (2023)

Cluster mean-field theory accurately predicts statistical properties of large-scale DNA methylation patterns
por: Kerr, Lyndsay, et al.
Publicado: (2022)

Multi-model forecasts of the ongoing Ebola epidemic in the Democratic Republic of Congo, March–October 2019
por: Roosa, Kimberlyn, et al.
Publicado: (2020)

Spatio-temporal surveillance and early detection of SARS-CoV-2 variants of concern: a retrospective analysis
por: Cavallaro, Massimo, et al.
Publicado: (2023)

Deciphering early-warning signals of SARS-CoV-2 elimination and resurgence from limited data at multiple scales
por: Parag, Kris V., et al.
Publicado: (2021)

Multi-scale dissection of wing transparency in the clearwing butterfly Phanus vitreus
por: Finet, Cédric, et al.
Publicado: (2023)

Detection of HIV transmission clusters from phylogenetic trees using a multi-state birth–death model
por: Barido-Sottani, Joëlle, et al.
Publicado: (2018)

On the impact of modelling assumptions in multi-scale, subject-specific models of aortic haemodynamics
por: Alastruey, Jordi, et al.
Publicado: (2016)

Stem cell competition in the gut: insights from multi-scale computational modelling
por: Thalheim, Torsten, et al.
Publicado: (2016)

Pareto rules for malaria super-spreaders and super-spreading
por: Cooper, Laura, et al.
Publicado: (2019)

Computational tools for clinical support: a multi-scale compliant model for haemodynamic simulations in an aortic dissection based on multi-modal imaging data
por: Bonfanti, Mirko, et al.
Publicado: (2017)

Evaluation of mechanistic and statistical methods in forecasting influenza-like illness
por: Kandula, Sasikiran, et al.
Publicado: (2018)

Inferring kinetic parameters of oscillatory gene regulation from single cell time-series data
por: Burton, Joshua, et al.
Publicado: (2021)

Dynamic switching of lateral inhibition spatial patterns
por: Hawley, Joshua, et al.
Publicado: (2022)

Large-scale molecular dynamics simulation of coupled dynamics of flow and glycocalyx: towards understanding atomic events on an endothelial cell surface
por: Jiang, Xi Zhuo, et al.
Publicado: (2017)

A massively multi-scale approach to characterizing tissue architecture by synchrotron micro-CT applied to the human placenta
por: Tun, W. M., et al.
Publicado: (2021)

Distinguishing between models of mammalian gene expression: telegraph-like models versus mechanistic models
por: Braichenko, Svitlana, et al.
Publicado: (2021)

Viral load and contact heterogeneity predict SARS-CoV-2 transmission and super-spreading events
por: Goyal, Ashish, et al.
Publicado: (2021)

Assessment of surface roughness and blood rheology on local coronary haemodynamics: a multi-scale computational fluid dynamics study
por: Owen, David G., et al.
Publicado: (2020)

Symbolic transfer entropy reveals the age structure of pandemic influenza transmission from high-volume influenza-like illness data
por: Kissler, Stephen M., et al.
Publicado: (2020)

Spatial super-spreaders and super-susceptibles in human movement networks
por: Chin, Wei Chien Benny, et al.
Publicado: (2020)

Reconciling early-outbreak estimates of the basic reproductive number and its uncertainty: framework and applications to the novel coronavirus (SARS-CoV-2) outbreak
por: Park, Sang Woo, et al.
Publicado: (2020)

Super-Spreader Identification Using Meta-Centrality
por: Madotto, Andrea, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_s5fjfar0vkj1ivttfb3238nt70