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Toxoplasma gondii Genotyping: A Closer Look Into Europe

Toxoplasma gondii is a major zoonotic agent which may cause harmful effects mainly in pregnant and immunocompromised hosts. Despite many efforts on its genetic characterization, an entirely clear picture of the population structure in Europe has not been achieved yet. The present study aimed to summ...

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Autores principales: Fernández-Escobar, Mercedes, Schares, Gereon, Maksimov, Pavlo, Joeres, Maike, Ortega-Mora, Luis Miguel, Calero-Bernal, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8984497/
https://www.ncbi.nlm.nih.gov/pubmed/35402301
http://dx.doi.org/10.3389/fcimb.2022.842595
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author Fernández-Escobar, Mercedes
Schares, Gereon
Maksimov, Pavlo
Joeres, Maike
Ortega-Mora, Luis Miguel
Calero-Bernal, Rafael
author_facet Fernández-Escobar, Mercedes
Schares, Gereon
Maksimov, Pavlo
Joeres, Maike
Ortega-Mora, Luis Miguel
Calero-Bernal, Rafael
author_sort Fernández-Escobar, Mercedes
collection PubMed
description Toxoplasma gondii is a major zoonotic agent which may cause harmful effects mainly in pregnant and immunocompromised hosts. Despite many efforts on its genetic characterization, an entirely clear picture of the population structure in Europe has not been achieved yet. The present study aimed to summarize the available genotyping information and to map the distribution of circulating strains. There is consensus on type II T. gondii genotypes prevailing in Europe, but the absence of harmonization in the use of typing methods limits detailed knowledge. Standardized, high-end typing tools and integrative strategies are needed to fill the gaps and complete an accurate image of the T. gondii genetic population in Europe.
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spelling pubmed-89844972022-04-07 Toxoplasma gondii Genotyping: A Closer Look Into Europe Fernández-Escobar, Mercedes Schares, Gereon Maksimov, Pavlo Joeres, Maike Ortega-Mora, Luis Miguel Calero-Bernal, Rafael Front Cell Infect Microbiol Cellular and Infection Microbiology Toxoplasma gondii is a major zoonotic agent which may cause harmful effects mainly in pregnant and immunocompromised hosts. Despite many efforts on its genetic characterization, an entirely clear picture of the population structure in Europe has not been achieved yet. The present study aimed to summarize the available genotyping information and to map the distribution of circulating strains. There is consensus on type II T. gondii genotypes prevailing in Europe, but the absence of harmonization in the use of typing methods limits detailed knowledge. Standardized, high-end typing tools and integrative strategies are needed to fill the gaps and complete an accurate image of the T. gondii genetic population in Europe. Frontiers Media S.A. 2022-03-23 /pmc/articles/PMC8984497/ /pubmed/35402301 http://dx.doi.org/10.3389/fcimb.2022.842595 Text en Copyright © 2022 Fernández-Escobar, Schares, Maksimov, Joeres, Ortega-Mora and Calero-Bernal https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cellular and Infection Microbiology
Fernández-Escobar, Mercedes
Schares, Gereon
Maksimov, Pavlo
Joeres, Maike
Ortega-Mora, Luis Miguel
Calero-Bernal, Rafael
Toxoplasma gondii Genotyping: A Closer Look Into Europe
title Toxoplasma gondii Genotyping: A Closer Look Into Europe
title_full Toxoplasma gondii Genotyping: A Closer Look Into Europe
title_fullStr Toxoplasma gondii Genotyping: A Closer Look Into Europe
title_full_unstemmed Toxoplasma gondii Genotyping: A Closer Look Into Europe
title_short Toxoplasma gondii Genotyping: A Closer Look Into Europe
title_sort toxoplasma gondii genotyping: a closer look into europe
topic Cellular and Infection Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8984497/
https://www.ncbi.nlm.nih.gov/pubmed/35402301
http://dx.doi.org/10.3389/fcimb.2022.842595
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