Palladium-catalyzed regioselective hydrosulfonylation of allenes with sulfinic acids

An atom-economic method of preparing allylic sulfones via hydrosulfonylation of allenes with sulfinic acids under Pd(0)-catalysis was reported. This process has a high degree of regio- and stereoselectivity, and provides the target product with a moderate to excellent yield. A wide range of nitrogen...

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Autores principales: Li, Luan-Ying, Leng, Bo-Rong, Li, Jia-Zhuo, Liu, Qing-Quan, Yu, Jianguang, Wei, Ping, Wang, De-Cai, Zhu, Yi-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8984952/
https://www.ncbi.nlm.nih.gov/pubmed/35424818
http://dx.doi.org/10.1039/d1ra09036d
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author Li, Luan-Ying
Leng, Bo-Rong
Li, Jia-Zhuo
Liu, Qing-Quan
Yu, Jianguang
Wei, Ping
Wang, De-Cai
Zhu, Yi-Long
author_facet Li, Luan-Ying
Leng, Bo-Rong
Li, Jia-Zhuo
Liu, Qing-Quan
Yu, Jianguang
Wei, Ping
Wang, De-Cai
Zhu, Yi-Long
author_sort Li, Luan-Ying
collection PubMed
description An atom-economic method of preparing allylic sulfones via hydrosulfonylation of allenes with sulfinic acids under Pd(0)-catalysis was reported. This process has a high degree of regio- and stereoselectivity, and provides the target product with a moderate to excellent yield. A wide range of nitrogen- or oxygen-containing linear E-allylic sulfones have been synthesized. With the support of experimental research, a possible mechanism was proposed.
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spelling pubmed-89849522022-04-13 Palladium-catalyzed regioselective hydrosulfonylation of allenes with sulfinic acids Li, Luan-Ying Leng, Bo-Rong Li, Jia-Zhuo Liu, Qing-Quan Yu, Jianguang Wei, Ping Wang, De-Cai Zhu, Yi-Long RSC Adv Chemistry An atom-economic method of preparing allylic sulfones via hydrosulfonylation of allenes with sulfinic acids under Pd(0)-catalysis was reported. This process has a high degree of regio- and stereoselectivity, and provides the target product with a moderate to excellent yield. A wide range of nitrogen- or oxygen-containing linear E-allylic sulfones have been synthesized. With the support of experimental research, a possible mechanism was proposed. The Royal Society of Chemistry 2022-03-18 /pmc/articles/PMC8984952/ /pubmed/35424818 http://dx.doi.org/10.1039/d1ra09036d Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Li, Luan-Ying
Leng, Bo-Rong
Li, Jia-Zhuo
Liu, Qing-Quan
Yu, Jianguang
Wei, Ping
Wang, De-Cai
Zhu, Yi-Long
Palladium-catalyzed regioselective hydrosulfonylation of allenes with sulfinic acids
title Palladium-catalyzed regioselective hydrosulfonylation of allenes with sulfinic acids
title_full Palladium-catalyzed regioselective hydrosulfonylation of allenes with sulfinic acids
title_fullStr Palladium-catalyzed regioselective hydrosulfonylation of allenes with sulfinic acids
title_full_unstemmed Palladium-catalyzed regioselective hydrosulfonylation of allenes with sulfinic acids
title_short Palladium-catalyzed regioselective hydrosulfonylation of allenes with sulfinic acids
title_sort palladium-catalyzed regioselective hydrosulfonylation of allenes with sulfinic acids
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8984952/
https://www.ncbi.nlm.nih.gov/pubmed/35424818
http://dx.doi.org/10.1039/d1ra09036d
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