Transcription Factor c-Maf Promotes Immunoregulation of Programmed Cell Death 1–Expressed CD8(+) T Cells in Multiple Sclerosis

BACKGROUND AND OBJECTIVES: Multiple sclerosis (MS) is an inflammatory demyelinating disease of the CNS. CD8(+) T cells are prominently found at inflammatory sites. Recent advances in understanding checkpoint molecules, including programmed cell death 1 (PD-1), expressed on CD8(+) T cells, highlight...

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Detalles Bibliográficos
Autores principales: Koto, Shusuke, Chihara, Norio, Akatani, Ritsu, Nakano, Hiroko, Hara, Atsushi, Sekiguchi, Kenji, Matsumoto, Riki, Toda, Tatsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985076/
https://www.ncbi.nlm.nih.gov/pubmed/35383094
http://dx.doi.org/10.1212/NXI.0000000000001166

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