Bakuchiol – a natural meroterpenoid: structure, isolation, synthesis and functionalization approaches

Bakuchiol is an emblematic meroterpene class of natural product extracted from Psoralea corylifolia. It has been reported to possess a broad range of biological and pharmacological properties and is considered as a leading biomolecule. It is highly desirable to devise an efficient approach to access...

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Autores principales: Adarsh Krishna, T. P., Edachery, Baldev, Athalathil, Sunil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985110/
https://www.ncbi.nlm.nih.gov/pubmed/35424800
http://dx.doi.org/10.1039/d1ra08771a
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author Adarsh Krishna, T. P.
Edachery, Baldev
Athalathil, Sunil
author_facet Adarsh Krishna, T. P.
Edachery, Baldev
Athalathil, Sunil
author_sort Adarsh Krishna, T. P.
collection PubMed
description Bakuchiol is an emblematic meroterpene class of natural product extracted from Psoralea corylifolia. It has been reported to possess a broad range of biological and pharmacological properties and is considered as a leading biomolecule. It is highly desirable to devise an efficient approach to access bakuchiol and its chemical biology applications. In this review we provided structural features, isolation methods, various chemical routes and late-stage functionalization (LSF) approaches for bakuchiol and its derivatives. Moreover, this review encompasses the structure–activity relationships (SAR), value-added contributions and future perspectives of bakuchiol
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spelling pubmed-89851102022-04-13 Bakuchiol – a natural meroterpenoid: structure, isolation, synthesis and functionalization approaches Adarsh Krishna, T. P. Edachery, Baldev Athalathil, Sunil RSC Adv Chemistry Bakuchiol is an emblematic meroterpene class of natural product extracted from Psoralea corylifolia. It has been reported to possess a broad range of biological and pharmacological properties and is considered as a leading biomolecule. It is highly desirable to devise an efficient approach to access bakuchiol and its chemical biology applications. In this review we provided structural features, isolation methods, various chemical routes and late-stage functionalization (LSF) approaches for bakuchiol and its derivatives. Moreover, this review encompasses the structure–activity relationships (SAR), value-added contributions and future perspectives of bakuchiol The Royal Society of Chemistry 2022-03-21 /pmc/articles/PMC8985110/ /pubmed/35424800 http://dx.doi.org/10.1039/d1ra08771a Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Adarsh Krishna, T. P.
Edachery, Baldev
Athalathil, Sunil
Bakuchiol – a natural meroterpenoid: structure, isolation, synthesis and functionalization approaches
title Bakuchiol – a natural meroterpenoid: structure, isolation, synthesis and functionalization approaches
title_full Bakuchiol – a natural meroterpenoid: structure, isolation, synthesis and functionalization approaches
title_fullStr Bakuchiol – a natural meroterpenoid: structure, isolation, synthesis and functionalization approaches
title_full_unstemmed Bakuchiol – a natural meroterpenoid: structure, isolation, synthesis and functionalization approaches
title_short Bakuchiol – a natural meroterpenoid: structure, isolation, synthesis and functionalization approaches
title_sort bakuchiol – a natural meroterpenoid: structure, isolation, synthesis and functionalization approaches
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985110/
https://www.ncbi.nlm.nih.gov/pubmed/35424800
http://dx.doi.org/10.1039/d1ra08771a
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