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Preparation and properties of a novel poly(lactic-acid)-based thermoplastic vulcanizate from both experiments and simulations

A novel bio-based thermoplastic vulcanizate (TPV) material consisting of poly(lactic acid) (PLA) and a novel polymeric slide ring material (SeRM) was fabricated via isocyanate-induced dynamic vulcanization. The microscopic morphology, thermal properties, biocompatibility, and mechanical properties o...

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Autores principales: Li, Xue, Kang, Hailan, Luo, Qiulan, Shen, Jianxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985119/
https://www.ncbi.nlm.nih.gov/pubmed/35424957
http://dx.doi.org/10.1039/d2ra00286h
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author Li, Xue
Kang, Hailan
Luo, Qiulan
Shen, Jianxiang
author_facet Li, Xue
Kang, Hailan
Luo, Qiulan
Shen, Jianxiang
author_sort Li, Xue
collection PubMed
description A novel bio-based thermoplastic vulcanizate (TPV) material consisting of poly(lactic acid) (PLA) and a novel polymeric slide ring material (SeRM) was fabricated via isocyanate-induced dynamic vulcanization. The microscopic morphology, thermal properties, biocompatibility, and mechanical properties of the SeRM/PLA TPV material were comprehensively investigated, in turn by transmission electron microscopy, differential scanning calorimetry, in vitro cytotoxicity test, electron tension machine, and molecular dynamics simulations. Phase inversion in TPV was observed during the dynamic vulcanization, and TEM images showed that SeRM particles that were dispersed in PLA continuous phase had an average diameter of 1–4 μm. Results also indicated that an optimum phase inversion morphology was obtained at the SeRM/PLA blending ratio of 70/30 w/w. Glass transition temperature of PLA was found to be slightly decreased, owing to the improvement in interface compatibility by chemically bonding the PCL side chains (of SeRM molecules) and PLA chains. The tensile strength and elongation at break of TPVs were approximately 14.7 MPa and 164%, respectively, at SeRM/PLA blending ratio of 70/30, owing to the unique sliding effect of SeRM molecules when subjected to deformations. Cytotoxicity test results proved that the bio-based TPVs were fully non-toxic to L929 cells. In such aspects we believe that the bio-based TPV can be a promising material in the biomedical applications as an alternative of traditional commodity plastics.
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spelling pubmed-89851192022-04-13 Preparation and properties of a novel poly(lactic-acid)-based thermoplastic vulcanizate from both experiments and simulations Li, Xue Kang, Hailan Luo, Qiulan Shen, Jianxiang RSC Adv Chemistry A novel bio-based thermoplastic vulcanizate (TPV) material consisting of poly(lactic acid) (PLA) and a novel polymeric slide ring material (SeRM) was fabricated via isocyanate-induced dynamic vulcanization. The microscopic morphology, thermal properties, biocompatibility, and mechanical properties of the SeRM/PLA TPV material were comprehensively investigated, in turn by transmission electron microscopy, differential scanning calorimetry, in vitro cytotoxicity test, electron tension machine, and molecular dynamics simulations. Phase inversion in TPV was observed during the dynamic vulcanization, and TEM images showed that SeRM particles that were dispersed in PLA continuous phase had an average diameter of 1–4 μm. Results also indicated that an optimum phase inversion morphology was obtained at the SeRM/PLA blending ratio of 70/30 w/w. Glass transition temperature of PLA was found to be slightly decreased, owing to the improvement in interface compatibility by chemically bonding the PCL side chains (of SeRM molecules) and PLA chains. The tensile strength and elongation at break of TPVs were approximately 14.7 MPa and 164%, respectively, at SeRM/PLA blending ratio of 70/30, owing to the unique sliding effect of SeRM molecules when subjected to deformations. Cytotoxicity test results proved that the bio-based TPVs were fully non-toxic to L929 cells. In such aspects we believe that the bio-based TPV can be a promising material in the biomedical applications as an alternative of traditional commodity plastics. The Royal Society of Chemistry 2022-03-25 /pmc/articles/PMC8985119/ /pubmed/35424957 http://dx.doi.org/10.1039/d2ra00286h Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Li, Xue
Kang, Hailan
Luo, Qiulan
Shen, Jianxiang
Preparation and properties of a novel poly(lactic-acid)-based thermoplastic vulcanizate from both experiments and simulations
title Preparation and properties of a novel poly(lactic-acid)-based thermoplastic vulcanizate from both experiments and simulations
title_full Preparation and properties of a novel poly(lactic-acid)-based thermoplastic vulcanizate from both experiments and simulations
title_fullStr Preparation and properties of a novel poly(lactic-acid)-based thermoplastic vulcanizate from both experiments and simulations
title_full_unstemmed Preparation and properties of a novel poly(lactic-acid)-based thermoplastic vulcanizate from both experiments and simulations
title_short Preparation and properties of a novel poly(lactic-acid)-based thermoplastic vulcanizate from both experiments and simulations
title_sort preparation and properties of a novel poly(lactic-acid)-based thermoplastic vulcanizate from both experiments and simulations
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985119/
https://www.ncbi.nlm.nih.gov/pubmed/35424957
http://dx.doi.org/10.1039/d2ra00286h
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