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Molecularly imprinted polymers via reversible addition–fragmentation chain-transfer synthesis in sensing and environmental applications

Molecularly imprinted polymers (MIP) have shown their potential as artificial and selective receptors for environmental monitoring. These materials can be tailor-made to achieve a specific binding event with a template through a chosen mechanism. They are capable of emulating the recognition capacit...

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Autores principales: Veloz Martínez, Irvin, Ek, Jackeline Iturbe, Ahn, Ethan C., Sustaita, Alan O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985154/
https://www.ncbi.nlm.nih.gov/pubmed/35424874
http://dx.doi.org/10.1039/d2ra00232a
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author Veloz Martínez, Irvin
Ek, Jackeline Iturbe
Ahn, Ethan C.
Sustaita, Alan O.
author_facet Veloz Martínez, Irvin
Ek, Jackeline Iturbe
Ahn, Ethan C.
Sustaita, Alan O.
author_sort Veloz Martínez, Irvin
collection PubMed
description Molecularly imprinted polymers (MIP) have shown their potential as artificial and selective receptors for environmental monitoring. These materials can be tailor-made to achieve a specific binding event with a template through a chosen mechanism. They are capable of emulating the recognition capacity of biological receptors with superior stability and versatility of integration in sensing platforms. Commonly, these polymers are produced by traditional free radical bulk polymerization (FRP) which may not be the most suitable for enhancing the intended properties due to the poor imprinting performance. To improve the imprinting technique and the polymer capabilities, controlled/living radical polymerization (CRP) has been used to overcome the main drawbacks of FRP. Combining CRP techniques such as RAFT (reversible addition–fragmentation chain transfer) with MIP has achieved higher selectivity, sensitivity, and sorption capacity of these polymers when implemented as the transductor element in sensors. The present work focuses on RAFT-MIP design and synthesis strategies to enhance the binding affinities and their implementation in environmental contaminant sensing applications.
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spelling pubmed-89851542022-04-13 Molecularly imprinted polymers via reversible addition–fragmentation chain-transfer synthesis in sensing and environmental applications Veloz Martínez, Irvin Ek, Jackeline Iturbe Ahn, Ethan C. Sustaita, Alan O. RSC Adv Chemistry Molecularly imprinted polymers (MIP) have shown their potential as artificial and selective receptors for environmental monitoring. These materials can be tailor-made to achieve a specific binding event with a template through a chosen mechanism. They are capable of emulating the recognition capacity of biological receptors with superior stability and versatility of integration in sensing platforms. Commonly, these polymers are produced by traditional free radical bulk polymerization (FRP) which may not be the most suitable for enhancing the intended properties due to the poor imprinting performance. To improve the imprinting technique and the polymer capabilities, controlled/living radical polymerization (CRP) has been used to overcome the main drawbacks of FRP. Combining CRP techniques such as RAFT (reversible addition–fragmentation chain transfer) with MIP has achieved higher selectivity, sensitivity, and sorption capacity of these polymers when implemented as the transductor element in sensors. The present work focuses on RAFT-MIP design and synthesis strategies to enhance the binding affinities and their implementation in environmental contaminant sensing applications. The Royal Society of Chemistry 2022-03-23 /pmc/articles/PMC8985154/ /pubmed/35424874 http://dx.doi.org/10.1039/d2ra00232a Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Veloz Martínez, Irvin
Ek, Jackeline Iturbe
Ahn, Ethan C.
Sustaita, Alan O.
Molecularly imprinted polymers via reversible addition–fragmentation chain-transfer synthesis in sensing and environmental applications
title Molecularly imprinted polymers via reversible addition–fragmentation chain-transfer synthesis in sensing and environmental applications
title_full Molecularly imprinted polymers via reversible addition–fragmentation chain-transfer synthesis in sensing and environmental applications
title_fullStr Molecularly imprinted polymers via reversible addition–fragmentation chain-transfer synthesis in sensing and environmental applications
title_full_unstemmed Molecularly imprinted polymers via reversible addition–fragmentation chain-transfer synthesis in sensing and environmental applications
title_short Molecularly imprinted polymers via reversible addition–fragmentation chain-transfer synthesis in sensing and environmental applications
title_sort molecularly imprinted polymers via reversible addition–fragmentation chain-transfer synthesis in sensing and environmental applications
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985154/
https://www.ncbi.nlm.nih.gov/pubmed/35424874
http://dx.doi.org/10.1039/d2ra00232a
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