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Molecularly imprinted polymers via reversible addition–fragmentation chain-transfer synthesis in sensing and environmental applications
Molecularly imprinted polymers (MIP) have shown their potential as artificial and selective receptors for environmental monitoring. These materials can be tailor-made to achieve a specific binding event with a template through a chosen mechanism. They are capable of emulating the recognition capacit...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985154/ https://www.ncbi.nlm.nih.gov/pubmed/35424874 http://dx.doi.org/10.1039/d2ra00232a |
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author | Veloz Martínez, Irvin Ek, Jackeline Iturbe Ahn, Ethan C. Sustaita, Alan O. |
author_facet | Veloz Martínez, Irvin Ek, Jackeline Iturbe Ahn, Ethan C. Sustaita, Alan O. |
author_sort | Veloz Martínez, Irvin |
collection | PubMed |
description | Molecularly imprinted polymers (MIP) have shown their potential as artificial and selective receptors for environmental monitoring. These materials can be tailor-made to achieve a specific binding event with a template through a chosen mechanism. They are capable of emulating the recognition capacity of biological receptors with superior stability and versatility of integration in sensing platforms. Commonly, these polymers are produced by traditional free radical bulk polymerization (FRP) which may not be the most suitable for enhancing the intended properties due to the poor imprinting performance. To improve the imprinting technique and the polymer capabilities, controlled/living radical polymerization (CRP) has been used to overcome the main drawbacks of FRP. Combining CRP techniques such as RAFT (reversible addition–fragmentation chain transfer) with MIP has achieved higher selectivity, sensitivity, and sorption capacity of these polymers when implemented as the transductor element in sensors. The present work focuses on RAFT-MIP design and synthesis strategies to enhance the binding affinities and their implementation in environmental contaminant sensing applications. |
format | Online Article Text |
id | pubmed-8985154 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | The Royal Society of Chemistry |
record_format | MEDLINE/PubMed |
spelling | pubmed-89851542022-04-13 Molecularly imprinted polymers via reversible addition–fragmentation chain-transfer synthesis in sensing and environmental applications Veloz Martínez, Irvin Ek, Jackeline Iturbe Ahn, Ethan C. Sustaita, Alan O. RSC Adv Chemistry Molecularly imprinted polymers (MIP) have shown their potential as artificial and selective receptors for environmental monitoring. These materials can be tailor-made to achieve a specific binding event with a template through a chosen mechanism. They are capable of emulating the recognition capacity of biological receptors with superior stability and versatility of integration in sensing platforms. Commonly, these polymers are produced by traditional free radical bulk polymerization (FRP) which may not be the most suitable for enhancing the intended properties due to the poor imprinting performance. To improve the imprinting technique and the polymer capabilities, controlled/living radical polymerization (CRP) has been used to overcome the main drawbacks of FRP. Combining CRP techniques such as RAFT (reversible addition–fragmentation chain transfer) with MIP has achieved higher selectivity, sensitivity, and sorption capacity of these polymers when implemented as the transductor element in sensors. The present work focuses on RAFT-MIP design and synthesis strategies to enhance the binding affinities and their implementation in environmental contaminant sensing applications. The Royal Society of Chemistry 2022-03-23 /pmc/articles/PMC8985154/ /pubmed/35424874 http://dx.doi.org/10.1039/d2ra00232a Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/ |
spellingShingle | Chemistry Veloz Martínez, Irvin Ek, Jackeline Iturbe Ahn, Ethan C. Sustaita, Alan O. Molecularly imprinted polymers via reversible addition–fragmentation chain-transfer synthesis in sensing and environmental applications |
title | Molecularly imprinted polymers via reversible addition–fragmentation chain-transfer synthesis in sensing and environmental applications |
title_full | Molecularly imprinted polymers via reversible addition–fragmentation chain-transfer synthesis in sensing and environmental applications |
title_fullStr | Molecularly imprinted polymers via reversible addition–fragmentation chain-transfer synthesis in sensing and environmental applications |
title_full_unstemmed | Molecularly imprinted polymers via reversible addition–fragmentation chain-transfer synthesis in sensing and environmental applications |
title_short | Molecularly imprinted polymers via reversible addition–fragmentation chain-transfer synthesis in sensing and environmental applications |
title_sort | molecularly imprinted polymers via reversible addition–fragmentation chain-transfer synthesis in sensing and environmental applications |
topic | Chemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985154/ https://www.ncbi.nlm.nih.gov/pubmed/35424874 http://dx.doi.org/10.1039/d2ra00232a |
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