Synthesis of 4-thiouridines with prodrug functionalization for RNA metabolic labeling

Metabolic labeling has emerged as a powerful tool to endow RNA with reactive handles allowing for subsequent chemical derivatization and processing. Recently, thiolated nucleosides, such as 4-thiouridine (4sU), have attracted great interest in metabolic labeling-based RNA sequencing approaches (TUC-...

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Detalles Bibliográficos
Autores principales: Moreno, Sarah, Brunner, Melanie, Delazer, Isabel, Rieder, Dietmar, Lusser, Alexandra, Micura, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985182/
https://www.ncbi.nlm.nih.gov/pubmed/35441143
http://dx.doi.org/10.1039/d2cb00001f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985182/
https://www.ncbi.nlm.nih.gov/pubmed/35441143
http://dx.doi.org/10.1039/d2cb00001f

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