The CSY-protecting group in the microwave-assisted synthesis of aggregation-prone peptides

This report describes the application of cyanosulfurylide (CSY)-protected aspartatic acid building blocks in microwave-assisted synthesis of aggregation-prone protein domains. We present a synthesis of Fmoc-Asp(CSY)-OH on a multigram scale, as well as procedures for the microwave-assisted synthesis...

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Detalles Bibliográficos
Autores principales: Pham, Truc Lam, Zilke, Jennifer, Müller, Christine Charlotte, Thomas, Franziska
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985196/
https://www.ncbi.nlm.nih.gov/pubmed/35441139
http://dx.doi.org/10.1039/d1cb00252j

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