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PPFIA4 promotes castration-resistant prostate cancer by enhancing mitochondrial metabolism through MTHFD2

BACKGROUND: The development of castration-resistant prostate cancer (CRPC) remains a major obstacle in the treatment of prostate cancer (PCa). Dysregulated mitochondrial function has been linked to the initiation and progression of diverse human cancers. Deciphering the novel molecular mechanisms un...

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Detalles Bibliográficos
Autores principales: Zhao, Ru, Feng, Tingting, Gao, Lin, Sun, Feifei, Zhou, Qianqian, Wang, Xin, Liu, Junmei, Zhang, Wenbo, Wang, Meng, Xiong, Xueting, Jia, Wenqiao, Chen, Weiwen, Wang, Lin, Han, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985307/
https://www.ncbi.nlm.nih.gov/pubmed/35382861
http://dx.doi.org/10.1186/s13046-022-02331-3