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Single-cell transcriptomics of the ventral posterolateral nucleus-enriched thalamic regions from HSV-1-infected mice reveal a novel microglia/microglia-like transcriptional response
BACKGROUND: Microglia participate in the immune response upon central nervous system (CNS) infections. However, the role of these cells during herpes simplex encephalitis (HSE) has not been fully characterized. We sought to identify different microglia/microglia-like cells and describe the potential...
Autores principales: | Uyar, Olus, Dominguez, Juan Manuel, Bordeleau, Maude, Lapeyre, Lina, Ibáñez, Fernando González, Vallières, Luc, Tremblay, Marie-Eve, Corbeil, Jacques, Boivin, Guy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985399/ https://www.ncbi.nlm.nih.gov/pubmed/35387656 http://dx.doi.org/10.1186/s12974-022-02437-7 |
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