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Alzheimer's disease as an autoimmune disorder of innate immunity endogenously modulated by tryptophan metabolites
INTRODUCTION: Alzheimer's disease (AD) is characterized by neurotoxic immuno‐inflammation concomitant with cytotoxic oligomerization of amyloid beta (Aβ) and tau, culminating in concurrent, interdependent immunopathic and proteopathic pathogeneses. METHODS: We performed a comprehensive series o...
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