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Timing and mode of intervention for patients with left sided valvular heart disease: an individualized approach

Left sided valvular heart disease poses major impact on life and lifestyle. Medical therapy merely palliates chronic severe valve disease and once symptoms or haemodynamic sequelae appear, life expectancy is markedly truncated. In this article, we review the mechanisms of valve pathology, latest evi...

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Detalles Bibliográficos
Autores principales: McConkey, Hannah, Zhao, Zhengang, Redwood, S, Chen, M, Prendergast, B D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985789/
https://www.ncbi.nlm.nih.gov/pubmed/35692702
http://dx.doi.org/10.1093/pcmedi/pby017
Descripción
Sumario:Left sided valvular heart disease poses major impact on life and lifestyle. Medical therapy merely palliates chronic severe valve disease and once symptoms or haemodynamic sequelae appear, life expectancy is markedly truncated. In this article, we review the mechanisms of valve pathology, latest evidence in the quest for pharmacological options, means by which to predict deterioration, and standard and novel treatment options.