Timing and mode of intervention for patients with left sided valvular heart disease: an individualized approach

Left sided valvular heart disease poses major impact on life and lifestyle. Medical therapy merely palliates chronic severe valve disease and once symptoms or haemodynamic sequelae appear, life expectancy is markedly truncated. In this article, we review the mechanisms of valve pathology, latest evi...

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Detalles Bibliográficos
Autores principales: McConkey, Hannah, Zhao, Zhengang, Redwood, S, Chen, M, Prendergast, B D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985789/
https://www.ncbi.nlm.nih.gov/pubmed/35692702
http://dx.doi.org/10.1093/pcmedi/pby017
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author McConkey, Hannah
Zhao, Zhengang
Redwood, S
Chen, M
Prendergast, B D
author_facet McConkey, Hannah
Zhao, Zhengang
Redwood, S
Chen, M
Prendergast, B D
author_sort McConkey, Hannah
collection PubMed
description Left sided valvular heart disease poses major impact on life and lifestyle. Medical therapy merely palliates chronic severe valve disease and once symptoms or haemodynamic sequelae appear, life expectancy is markedly truncated. In this article, we review the mechanisms of valve pathology, latest evidence in the quest for pharmacological options, means by which to predict deterioration, and standard and novel treatment options.
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spelling pubmed-89857892022-06-10 Timing and mode of intervention for patients with left sided valvular heart disease: an individualized approach McConkey, Hannah Zhao, Zhengang Redwood, S Chen, M Prendergast, B D Precis Clin Med Review Left sided valvular heart disease poses major impact on life and lifestyle. Medical therapy merely palliates chronic severe valve disease and once symptoms or haemodynamic sequelae appear, life expectancy is markedly truncated. In this article, we review the mechanisms of valve pathology, latest evidence in the quest for pharmacological options, means by which to predict deterioration, and standard and novel treatment options. Oxford University Press 2018-12 2018-12-19 /pmc/articles/PMC8985789/ /pubmed/35692702 http://dx.doi.org/10.1093/pcmedi/pby017 Text en © The Author(s) 2018. Published by Oxford University Press on behalf of West China School of Medicine & West China Hospital of Sichuan University. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Review
McConkey, Hannah
Zhao, Zhengang
Redwood, S
Chen, M
Prendergast, B D
Timing and mode of intervention for patients with left sided valvular heart disease: an individualized approach
title Timing and mode of intervention for patients with left sided valvular heart disease: an individualized approach
title_full Timing and mode of intervention for patients with left sided valvular heart disease: an individualized approach
title_fullStr Timing and mode of intervention for patients with left sided valvular heart disease: an individualized approach
title_full_unstemmed Timing and mode of intervention for patients with left sided valvular heart disease: an individualized approach
title_short Timing and mode of intervention for patients with left sided valvular heart disease: an individualized approach
title_sort timing and mode of intervention for patients with left sided valvular heart disease: an individualized approach
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985789/
https://www.ncbi.nlm.nih.gov/pubmed/35692702
http://dx.doi.org/10.1093/pcmedi/pby017
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