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Electrophysiological characteristics of non-pulmonary vein triggers excluding origins from the superior vena cava and left atrial posterior wall: Lessons from the self-reference mapping technique
BACKGROUND: The detailed electrophysiological characteristics of atrial fibrillation (AF) initiating non-pulmonary vein (PV) triggers excluding origins from the superior vena cava (SVC) and left atrial posterior wall (LAPW) (Non-PV-SVC-LAPW triggers) remain unclear. This study aimed to clarify the d...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985937/ https://www.ncbi.nlm.nih.gov/pubmed/35385530 http://dx.doi.org/10.1371/journal.pone.0263938 |
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author | Matsunaga-Lee, Yasuharu Egami, Yasuyuki Matsumoto, Sen Masunaga, Nobutaka Ukita, Kohei Kawamura, Akito Nakamura, Hitoshi Matsuhiro, Yutaka Yasumoto, Koji Tsuda, Masaki Okamoto, Naotaka Yano, Masamichi Takano, Yuzuru Sakata, Yasushi Nishino, Masami Tanouchi, Jun |
author_facet | Matsunaga-Lee, Yasuharu Egami, Yasuyuki Matsumoto, Sen Masunaga, Nobutaka Ukita, Kohei Kawamura, Akito Nakamura, Hitoshi Matsuhiro, Yutaka Yasumoto, Koji Tsuda, Masaki Okamoto, Naotaka Yano, Masamichi Takano, Yuzuru Sakata, Yasushi Nishino, Masami Tanouchi, Jun |
author_sort | Matsunaga-Lee, Yasuharu |
collection | PubMed |
description | BACKGROUND: The detailed electrophysiological characteristics of atrial fibrillation (AF) initiating non-pulmonary vein (PV) triggers excluding origins from the superior vena cava (SVC) and left atrial posterior wall (LAPW) (Non-PV-SVC-LAPW triggers) remain unclear. This study aimed to clarify the detailed electrophysiological characteristics of non-PV-SVC-LAPW triggers. METHODS: Among 446 AF ablation procedures at 2 institutions, patients with reproducible AF initiating non-PV-SVC-LAPW triggers were retrospectively enrolled. The trigger origin was mapped using the self-reference mapping technique. The following electrophysiological parameters were evaluated: the voltage during sinus rhythm and at the onset of AF at the earliest activation site, coupling interval of the trigger between the prior sinus rhythm and AF trigger, and voltage change ratio defined as the trigger voltage at the onset of AF divided by the sinus voltage. RESULTS: Detailed electrophysiological data were obtained at 28 triggers in 21 patients. The median trigger voltage at the onset of AF was 0.16mV and median trigger coupling interval 182msec. Normal sinus voltages (≧0.5mV) were observed at 16 triggers and low voltages (<0.5mV) at 12 triggers. The voltage change ratio was significantly lower for the normal sinus voltage than low sinus voltage (0.20 vs. 0.60, p = 0.002). The trigger coupling intervals were comparable between the normal sinus voltage and low sinus voltage (170ms vs. 185ms, p = 0.353). CONCLUSIONS: The trigger voltage at the onset of AF was low, regardless of whether the sinus voltage of the trigger was preserved or low. |
format | Online Article Text |
id | pubmed-8985937 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-89859372022-04-07 Electrophysiological characteristics of non-pulmonary vein triggers excluding origins from the superior vena cava and left atrial posterior wall: Lessons from the self-reference mapping technique Matsunaga-Lee, Yasuharu Egami, Yasuyuki Matsumoto, Sen Masunaga, Nobutaka Ukita, Kohei Kawamura, Akito Nakamura, Hitoshi Matsuhiro, Yutaka Yasumoto, Koji Tsuda, Masaki Okamoto, Naotaka Yano, Masamichi Takano, Yuzuru Sakata, Yasushi Nishino, Masami Tanouchi, Jun PLoS One Research Article BACKGROUND: The detailed electrophysiological characteristics of atrial fibrillation (AF) initiating non-pulmonary vein (PV) triggers excluding origins from the superior vena cava (SVC) and left atrial posterior wall (LAPW) (Non-PV-SVC-LAPW triggers) remain unclear. This study aimed to clarify the detailed electrophysiological characteristics of non-PV-SVC-LAPW triggers. METHODS: Among 446 AF ablation procedures at 2 institutions, patients with reproducible AF initiating non-PV-SVC-LAPW triggers were retrospectively enrolled. The trigger origin was mapped using the self-reference mapping technique. The following electrophysiological parameters were evaluated: the voltage during sinus rhythm and at the onset of AF at the earliest activation site, coupling interval of the trigger between the prior sinus rhythm and AF trigger, and voltage change ratio defined as the trigger voltage at the onset of AF divided by the sinus voltage. RESULTS: Detailed electrophysiological data were obtained at 28 triggers in 21 patients. The median trigger voltage at the onset of AF was 0.16mV and median trigger coupling interval 182msec. Normal sinus voltages (≧0.5mV) were observed at 16 triggers and low voltages (<0.5mV) at 12 triggers. The voltage change ratio was significantly lower for the normal sinus voltage than low sinus voltage (0.20 vs. 0.60, p = 0.002). The trigger coupling intervals were comparable between the normal sinus voltage and low sinus voltage (170ms vs. 185ms, p = 0.353). CONCLUSIONS: The trigger voltage at the onset of AF was low, regardless of whether the sinus voltage of the trigger was preserved or low. Public Library of Science 2022-04-06 /pmc/articles/PMC8985937/ /pubmed/35385530 http://dx.doi.org/10.1371/journal.pone.0263938 Text en © 2022 Matsunaga-Lee et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Matsunaga-Lee, Yasuharu Egami, Yasuyuki Matsumoto, Sen Masunaga, Nobutaka Ukita, Kohei Kawamura, Akito Nakamura, Hitoshi Matsuhiro, Yutaka Yasumoto, Koji Tsuda, Masaki Okamoto, Naotaka Yano, Masamichi Takano, Yuzuru Sakata, Yasushi Nishino, Masami Tanouchi, Jun Electrophysiological characteristics of non-pulmonary vein triggers excluding origins from the superior vena cava and left atrial posterior wall: Lessons from the self-reference mapping technique |
title | Electrophysiological characteristics of non-pulmonary vein triggers excluding origins from the superior vena cava and left atrial posterior wall: Lessons from the self-reference mapping technique |
title_full | Electrophysiological characteristics of non-pulmonary vein triggers excluding origins from the superior vena cava and left atrial posterior wall: Lessons from the self-reference mapping technique |
title_fullStr | Electrophysiological characteristics of non-pulmonary vein triggers excluding origins from the superior vena cava and left atrial posterior wall: Lessons from the self-reference mapping technique |
title_full_unstemmed | Electrophysiological characteristics of non-pulmonary vein triggers excluding origins from the superior vena cava and left atrial posterior wall: Lessons from the self-reference mapping technique |
title_short | Electrophysiological characteristics of non-pulmonary vein triggers excluding origins from the superior vena cava and left atrial posterior wall: Lessons from the self-reference mapping technique |
title_sort | electrophysiological characteristics of non-pulmonary vein triggers excluding origins from the superior vena cava and left atrial posterior wall: lessons from the self-reference mapping technique |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985937/ https://www.ncbi.nlm.nih.gov/pubmed/35385530 http://dx.doi.org/10.1371/journal.pone.0263938 |
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