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Mutations in the acetylation hotspots of Rbl2 are associated with increased risk of breast cancer

Retinoblastoma like protein-2 (Rbl2) is functionally regulated by phosphorylation and acetylation. Previously, we demonstrated that lysine K1083 (K1079 in human Rbl2) is a potential target for acetylation but its functional role remains elusive. We investigated alterations in human Rbl2 gene specifi...

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Detalles Bibliográficos
Autores principales: Ullah, Farman, Khurshid, Nadia, Fatimi, Qaiser, Loidl, Peter, Saeed, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985964/
https://www.ncbi.nlm.nih.gov/pubmed/35385527
http://dx.doi.org/10.1371/journal.pone.0266196