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A novel CD4 knockout mouse strain with a spontaneous frameshift mutation in the CD4 locus
T cells express co-receptors CD4 and CD8, which are involved in the recognition of antigen presented to T cell receptors. The expression of CD4 in thymic hematopoietic cells is crucial for the thymic development and selection of T cells. In this study, we identified a novel CD4 mutant allele that em...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985997/ https://www.ncbi.nlm.nih.gov/pubmed/35385550 http://dx.doi.org/10.1371/journal.pone.0266589 |