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Low cost multifunctional 3D printed image quality and dose verification phantom for an image-guided radiotherapy system

PURPOSE: Image-guided radiation therapy (IGRT) is used to precisely deliver radiation to a tumour to reduce the possible damage to the surrounding normal tissues. Clinics use various quality assurance (QA) equipment to ensure that the performance of the IGRT system meets the international standards...

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Autores principales: Wu, Jian-Kuen, Yu, Min-Chin, Chen, Shih-Han, Liao, Shu-Hsien, Wang, Yu-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986000/
https://www.ncbi.nlm.nih.gov/pubmed/35385553
http://dx.doi.org/10.1371/journal.pone.0266604
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author Wu, Jian-Kuen
Yu, Min-Chin
Chen, Shih-Han
Liao, Shu-Hsien
Wang, Yu-Jen
author_facet Wu, Jian-Kuen
Yu, Min-Chin
Chen, Shih-Han
Liao, Shu-Hsien
Wang, Yu-Jen
author_sort Wu, Jian-Kuen
collection PubMed
description PURPOSE: Image-guided radiation therapy (IGRT) is used to precisely deliver radiation to a tumour to reduce the possible damage to the surrounding normal tissues. Clinics use various quality assurance (QA) equipment to ensure that the performance of the IGRT system meets the international standards set for the system. The objective of this study was to develop a low-cost and multipurpose module for evaluating image quality and dose. METHODS: A multipurpose phantom was designed to meet the clinical requirements of high accuracy, easy setup, and calibration. The outer shell of the phantom was fabricated using acrylic. Three dimensional (3D) printing technology was used to fabricate inner slabs with the characteristics of high spatial resolution, low-contrast detectability, a 3D grid, and liquid-filled uniformity. All materials were compatible with magnetic resonance (MR). Computed tomography (CT) simulator and linear accelerator (LINAC) modules were developed and validated. RESULTS: The uniformity slab filled with water is ideal for the assessment of Hounsfield units, whereas that filled with wax is suitable for consistency checks. The high-spatial-resolution slab enables measurements with a resolution up to 5 lp/cm. The low-contrast detectability slab contains rods of 5 different sizes that can be clearly visualised. These components meet the American College of Radiology (ACR) standards for QA of CT simulators and LINACs. CONCLUSIONS: The multifunctional phantom module meets the ACR recommended QA guidelines and is suitable for both LINACs and CT-sim. Further measurements in an MR simulator and an MR linear accelerator (MR-LINAC) will be arranged in the future.
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spelling pubmed-89860002022-04-07 Low cost multifunctional 3D printed image quality and dose verification phantom for an image-guided radiotherapy system Wu, Jian-Kuen Yu, Min-Chin Chen, Shih-Han Liao, Shu-Hsien Wang, Yu-Jen PLoS One Research Article PURPOSE: Image-guided radiation therapy (IGRT) is used to precisely deliver radiation to a tumour to reduce the possible damage to the surrounding normal tissues. Clinics use various quality assurance (QA) equipment to ensure that the performance of the IGRT system meets the international standards set for the system. The objective of this study was to develop a low-cost and multipurpose module for evaluating image quality and dose. METHODS: A multipurpose phantom was designed to meet the clinical requirements of high accuracy, easy setup, and calibration. The outer shell of the phantom was fabricated using acrylic. Three dimensional (3D) printing technology was used to fabricate inner slabs with the characteristics of high spatial resolution, low-contrast detectability, a 3D grid, and liquid-filled uniformity. All materials were compatible with magnetic resonance (MR). Computed tomography (CT) simulator and linear accelerator (LINAC) modules were developed and validated. RESULTS: The uniformity slab filled with water is ideal for the assessment of Hounsfield units, whereas that filled with wax is suitable for consistency checks. The high-spatial-resolution slab enables measurements with a resolution up to 5 lp/cm. The low-contrast detectability slab contains rods of 5 different sizes that can be clearly visualised. These components meet the American College of Radiology (ACR) standards for QA of CT simulators and LINACs. CONCLUSIONS: The multifunctional phantom module meets the ACR recommended QA guidelines and is suitable for both LINACs and CT-sim. Further measurements in an MR simulator and an MR linear accelerator (MR-LINAC) will be arranged in the future. Public Library of Science 2022-04-06 /pmc/articles/PMC8986000/ /pubmed/35385553 http://dx.doi.org/10.1371/journal.pone.0266604 Text en © 2022 Wu et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Wu, Jian-Kuen
Yu, Min-Chin
Chen, Shih-Han
Liao, Shu-Hsien
Wang, Yu-Jen
Low cost multifunctional 3D printed image quality and dose verification phantom for an image-guided radiotherapy system
title Low cost multifunctional 3D printed image quality and dose verification phantom for an image-guided radiotherapy system
title_full Low cost multifunctional 3D printed image quality and dose verification phantom for an image-guided radiotherapy system
title_fullStr Low cost multifunctional 3D printed image quality and dose verification phantom for an image-guided radiotherapy system
title_full_unstemmed Low cost multifunctional 3D printed image quality and dose verification phantom for an image-guided radiotherapy system
title_short Low cost multifunctional 3D printed image quality and dose verification phantom for an image-guided radiotherapy system
title_sort low cost multifunctional 3d printed image quality and dose verification phantom for an image-guided radiotherapy system
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986000/
https://www.ncbi.nlm.nih.gov/pubmed/35385553
http://dx.doi.org/10.1371/journal.pone.0266604
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