Cilia proteins are biomarkers of altered flow in the vasculature

Cilia, microtubule-based organelles that project from the apical luminal surface of endothelial cells (ECs), are widely regarded as low-flow sensors. Previous reports suggest that upon high shear stress, cilia on the EC surface are lost, and more recent evidence suggests that deciliation—the physica...

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Detalles Bibliográficos
Autores principales: Gupta, Ankan, Thirugnanam, Karthikeyan, Thamilarasan, Madhan, Mohieldin, Ashraf M., Zedan, Hadeel T., Prabhudesai, Shubhangi, Griffin, Meghan R., Spearman, Andrew D., Pan, Amy, Palecek, Sean P., Yalcin, Huseyin C., Nauli, Surya M., Rarick, Kevin R., Zennadi, Rahima, Ramchandran, Ramani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986075/
https://www.ncbi.nlm.nih.gov/pubmed/35143420
http://dx.doi.org/10.1172/jci.insight.151813

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